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Regional cerebral blood flow asymmetries in a group of 189 normal subjects at rest

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Summary

Regional cerebral blood flow (rCBF) asymmetries were studied in 189 subjects (96 males and 93 females) at rest with the133Xenon inhalation method using a fixed detector system. rCBF asymmetries in the resting condition were very small, nevertheless a significant (p<0.001) effect for their topographical distribution was present, reflecting higher rCBF in the right fronto-temporal and left parieto-occipital regions. rCBF asymmetries were not correlated with age, and there were no significant differences between males and females. Asymmetries are therefore useful from a statistical point of view in detecting rCBF abnormalities in the resting condition: they are more stable than absolute values in normal subjects and no matching according to age or sex is required when statistical comparisons are performed.

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Authors and Affiliations

  1. Institute of Neurophysiopathology, University, and Center for Cerebral Neurophysiology of the National Research Council (CNR), Genoa, Italy

    Guido Rodriguez, Fabrizio De Carli, Stefano Francione, Stefano Marenco, Flavio Nobili & Guido Rosadini

  2. NIMH Neuroscience Center at St. Elizabeth's, Washington DC, USA

    Richard Coppola

  3. Department of Psychogeriatrics, Lund, Sweden

    Jarl Risberg & Siegge Warkentin

Authors
  1. Guido Rodriguez
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  2. Richard Coppola
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  3. Fabrizio De Carli
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  4. Stefano Francione
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  5. Stefano Marenco
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  6. Flavio Nobili
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  7. Jarl Risberg
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  8. Guido Rosadini
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  9. Siegge Warkentin
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Dedicated to Professor Carlo Loeb (Genoa, Italy) on the occasion of his retirement.

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Rodriguez, G., Coppola, R., De Carli, F. et al. Regional cerebral blood flow asymmetries in a group of 189 normal subjects at rest. Brain Topogr 4, 57–63 (1991). https://doi.org/10.1007/BF01129666

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