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Advances in neuromagnetic instrumentation and studies of spontaneous brain activity

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Summary

Rapid progress in neuromagnetic technology has been achieved during the past two years with the introduction of a method for accurately indicating magnetic sensor locations with respect to a head-based coordinate system and the advent of refrigerator-cooled sensors and larger arrays of sensors. These make possible the real-time monitoring of evoked activity at several widely separated locations over the scalp, thus revealing sequential activity in, e.g., sensory-motor tasks. Arrays of magnetic sensors also provide sufficient information to locate the sources of spontaneous activity, such as alpha rhythm. The locations of discrete generators (alphons) of individual alpha spindles is now possible with an array of 14 sensors. Mapping techniques with a 5-sensor system have revealed preferential suppression of alpha activity within certain regions of the occipital lobe to tasks involving mental comparisons of abstract figures. These studies provide evidence that the machinery of visual cortex is involved in mental imagery.

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Authors and Affiliations

  1. Neuromagnetism Laboratory of the Departments of Physics and Psychology and Center for Neural Science, New York University, 2 Washington Place, 10003, New York, NY, USA

    Samuel J. Williamson & Lloyd Kaufman

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  1. Samuel J. Williamson
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  2. Lloyd Kaufman
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Additional information

This work was supported in part by Air Force Office of Scientific Research Grants AFOSR-84-0313, F49620-88-K-0004, and F49620-86-C-0131. We thank Dr. Jia-Zhu Wang for invaluable help with software development, Dr. D.S. Buchanan for calibrating the sensors, Dr. C. Salustri for helpful advice, and P. Fusco for technical assistance.

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Williamson, S.J., Kaufman, L. Advances in neuromagnetic instrumentation and studies of spontaneous brain activity. Brain Topogr 2, 129–139 (1989). https://doi.org/10.1007/BF01128850

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