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Erste tierexperimentelle und klinische Erfahrungen mit bioaktiver Glaskeramik in der rekonstruktiven Mittelohrchirurgie

Bioactive glass ceramics in reconstructive surgery of the middle ear. First experimental studies in animals and clinical findings

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Summary

The bioactive glass ceramic material (Ceravital) is fully accepted in osseous areas without formation of surrounding fibrous tissue; it is fixed by direct chemical bond. The use of this material in ENT surgery was tested in animals. In 70 rabbit ears, defects were inflicted on the tympanic membrane, ossicular chain and posterior wall of the external auditory meatus. Using standard tympanoplastic procedures, these defects were reconstructed using glass ceramic implants. The histological examinations of the preparations, which were embedded in Methylmetacrylate were performed using transmission light microscopy and fluorescence microscopy with incident light. The reactions between the implant and the host tissue, e.g., mucous membrane, free transplanted fascia and skin, were examined. In 85 patients Ceravital implants were used to reconstruct the ossicular chain and the posterior meatal wall of the outer ear canal. Functional results were satisfactory. No disturbances in woundhealing were observed.

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Die Untersuchungen werden von der Deutschen Forschungsgemeinschaft unterstützt

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Reck, R. Erste tierexperimentelle und klinische Erfahrungen mit bioaktiver Glaskeramik in der rekonstruktiven Mittelohrchirurgie. Arch Otorhinolaryngol 223, 369–373 (1979). https://doi.org/10.1007/BF01109585

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  • DOI: https://doi.org/10.1007/BF01109585

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