Summary
Intranuclear inclusions in neurons of the rat cochlear nucleus are described. The inclusions are equivalent to the ‘rodlets’ of the classical microscopists and ultrastructurally are of two types: rodshaped and sheet-shaped. The rods and sheets of the cochlear nucleus increase in frequency with age and are extremely common in adult and aged animals. Each inclusion is an aggregate of fine filaments approximately 70 Å in diameter. A rod consists of a bundle of parallel filaments; a sheet consists of a stepwise array of pairs of filamentous layers.
The literature on these inclusions is reviewed. They have now been seen in a wide enough variety of species and loci to be considered a common, rather than a remarkable, nuclear inclusion, although they are by no means universal. The evidence to date does not convincingly establish them as pathological entities.
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Feldman, M.L., Peters, A. Intranuclear rods and sheets in rat cochlear nucleus. J Neurocytol 1, 109–127 (1972). https://doi.org/10.1007/BF01099179
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DOI: https://doi.org/10.1007/BF01099179