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Studies on the fine structural localization of zinc-iodide-osmium reaction in the brain. II. Some characteristics of localization in certain identified synapses

  • Published:
Journal of Neurocytology

Summary

Samples of the olfactory bulb and cerebellar cortex from rats were impregnated in zinc-iodide-osmium (ZIO) solution. The fine structural localization of ZIO impregnation product was studied and, in addition, the percentage distribution of ZIO-positive synaptic vesicles was ascertained in certain synapses of known function. Spherical vesicles, particularly in aldehyde-prefixed material, were found to be more resistant to ZIO impregnation than ovoid vesicles, both in dendro-dendritic and in axodendritic synapses.

The different ZIO reactivity of synaptic vesicles in excitatory and inhibitory synapses, apart from reflecting an important difference in the chemical composition of synaptic vesicles, may offer a new method for characterizing synapses in relation to certain functions.

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Author notes

  1. Norbert Hálasz

    Present address: Department of Histology, Karolinska Institutet, Sweden

Authors and Affiliations

  1. Institute of Biophysics, Biological Research Center Szeged, Hungary

    Norbert Hálasz, Ferenc Joó & Árpád Párducz

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  1. Norbert Hálasz
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  2. Ferenc Joó
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  3. Árpád Párducz
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Hálasz, N., Joó, F. & Párducz, Á. Studies on the fine structural localization of zinc-iodide-osmium reaction in the brain. II. Some characteristics of localization in certain identified synapses. J Neurocytol 3, 557–566 (1974). https://doi.org/10.1007/BF01097624

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  • DOI: https://doi.org/10.1007/BF01097624

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