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Effect of boiled barley-rice-feeding in hypercholesterolemic and normolipemic subjects

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Abstract

Barley contains approximately 10% dietary fiber and is easily cooked with rice, the dominant cereal in Japan, to increase the intake of dietary fiber. This research involved three experiments to examine the influence of barley on blood lipids in human subjects. All subjects received a boiled barley-rice (50/50 w/w mix) supplement two times per day in place of rice for 2 or 4 weeks. In the normolipemic subjects, serum lipids were unaffected by the ingestion of barley for 4 weeks. In twenty hypercholesterolemic men aged 41 ± 5 years, the ingestion of barley was associated with a significant fall in serum total cholesterol, LDL-cholesterol, phospholipids and LDL and VLDL-lipoproteins. In seven mildly hypercholesterolemic women aged 56±7 years, a significant improvement of serum lipid profiles was observed. The present study suggests the possibility that the ingestion of barley-rice could lower serum lipids in hypercholesterolemic subjects.

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References

  1. Anderson JW, Bridges SR, Tietyen J, Gustafson NJ (1989) Dietary fiber content of a simulated American diet and selected research diets. Am J Clin Nutr 49: 352–357.

    PubMed  Google Scholar 

  2. Federal Register, January 6, 1993, volume 58(3), book II, page 2302–2964.

  3. National Advisory Committee on Nutrition Education (1983) Proposals for nutritional guidances for health education in Britain. Lancet 12: 835–837.

    Google Scholar 

  4. Ministry of Health and Welfare (1994) The Japanese Recommended Dietary Allowance, 5th edn (in Japanese).

  5. Nishimune T, Sumino T, Konishi Y, et al (1993) Dietary fiber intake of Japanese younger generations and the recommended daily allowance. J Nutr Sci Vitaminol 39: 263–278.

    PubMed  Google Scholar 

  6. Sato J, Osawa I, Hattori Y, Oshida Y, Sato Y (1990) Effects of dietary fiber on carbohydrate metabolism: A study in healthy subjects and diabetic patients. Nagoya J Health, Physical Fitness, Sports 13: 75–78 (in Japanese).

    Google Scholar 

  7. Ikegami S, Tsuchihashi F, Nakamura K, Innami S (1991) Effects of barley on development of experimental diabetes in rats. J Jpn Soc Nutr Food Sci 44: 447–454 (in Japanese).

    Google Scholar 

  8. Takase S, Kurihara H, Michi K (1970) Effect of cereals, especially barley on plasma cholesterol content. J Jpn Soc Nutr Food Sci 23: 426–429 (in Japanese)

    Google Scholar 

  9. Newman RK, Lewis SE, Newman CW, Boik RJ, Ramage RT (1989) Hypocholesterolemic effect of barley food on healthy men. Nutr Rep. Int 39: 650–659.

    Google Scholar 

  10. McIntosh GH, Whyte J, McArthur R, Nestel PJ (1991) Barley and wheat foods: Influence on plasma cholesterol concentrations in hypercholesterolemic men. Am J Clin Nutr 53: 1205–1209.

    PubMed  Google Scholar 

  11. Nagahara T, Iwao H, Kubo S (1964) Analytical methods of food components. Tokyo: Shibata Publishers (in Japanese).

    Google Scholar 

  12. AOAC (1985) Changes in methods: Total dietary fiber in foods, enzymatic-gravimetric method. J Assoc Off Anal Chem 68: 339.

    Google Scholar 

  13. NUT (1991) Nutrition Calculation Software, Version 2.0. Nagahama: Human Science Laboratory.

    Google Scholar 

  14. Science and Technology Agency, Resources Council (1992) Standard Table of Food Composition in Japan-Dietary Fiber.

  15. Friedwald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma without the use of preparative ultracentrifuge. Clin Chem 18: 499–502.

    PubMed  Google Scholar 

  16. Yagi K (1984) Assay of modes of biological damages improved byO 2 [39] assay for blood plasma or serum. Methods Enzymol 105: 328–331.

    PubMed  Google Scholar 

  17. Oda T, Aoe S, Sanada H, Ayano Y (1992) Effects of oat, barley and wheat on liver and plasma cholesterol concentrations in cholesterol-fed rats. J Jpn Soc Nutr Food Sci 45: 560–563 (in Japanese).

    Google Scholar 

  18. Qureshi AA, Burger WC, Prentice N, Bird HR, Sunde ML (1980) Regulation of lipid metabolism in chick liver by dietary cereals. J Nutr 110: 388–393.

    PubMed  Google Scholar 

  19. Fadel JG, Newman RK, Newman CW Barnes AE (1987) Hypocholesterolemic effects of beta-glucans in different barley diets fed to broiler chicks. Nutr Rep Intern 35: 1049–1058.

    Google Scholar 

  20. Wood PJ, Paton D, Siddiqui IR (1976) Determination of β-glucan in oat and barley. Cereal Chem 54: 524–533.

    Google Scholar 

  21. Newman RK, Newman CW, Hofer PJ, Barnes AE (1991) Growth and lipid metabolism as affected by feeding of hull-less barley with and without supplemental β-glucanase. Plant Foods Hum Nutr 41: 371–380.

    PubMed  Google Scholar 

  22. Wang L, Newman RK, Newman CW, Hofer PJ (1992) Barley β-glucans alter intestinal viscosity and reduce plasma cholesterol concentrations in chicks. J Nutr 122: 2292–2297.

    PubMed  Google Scholar 

  23. Oda T, Aoe S, Sanada H, Ayano Y (1993) Effects of soluble and insoluble fiber preparations isolated from oat, barley, and wheat on liver cholesterol accumulation in cholesterolfed rats. J Nutr Sci Vitamino 39: 73–79.

    Google Scholar 

  24. Davidson MH, Dugan LD, Burns JH, Bova J, Story K, Drennan KB (1991) The hypochlesterolemic effects of β-glucan in oatmeal and oat bran. J Am Med Assoc 265: 1833–1839.

    Google Scholar 

  25. Wang L, Newman RK, Newman CW, Jackson LL, Hofer PJ (1993) Tocotrienol and fatty acid composition of barley oil and their effect on lipid metabolism. Plant Foods Hum Nutr 43: 9–17.

    PubMed  Google Scholar 

  26. Esterbauer H, Gebicki J, Puhl H, Jurgens G (1992) The role of lipid peroxidation and antioxidants in oxidative modification of low density lipoproteins. Free Radical Biol Med 13: 34–90.

    Google Scholar 

  27. Qureshi AA, Burger WC, Peterson DM, Elson CE (1986) The structure of an inhibitor of cholesterol biosynthesis isolated from barley. J Biol Chem 261: 10544–10550.

    PubMed  Google Scholar 

  28. Swin JF, Rouse IL, Curley CB, Soks FM (1990) Comparison of the effects of oat bran and low-fiber wheat on serum lipoprotein levels and blood pressure. N Engl J Med 322: 147–152.

    PubMed  Google Scholar 

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Ikegami, S., Tomita, M., Honda, S. et al. Effect of boiled barley-rice-feeding in hypercholesterolemic and normolipemic subjects. Plant Food Hum Nutr 49, 317–328 (1996). https://doi.org/10.1007/BF01091981

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