Abstract
Differential effects of one or more genes in the nonpseudoautosomal region of the DBA1 and C57BL10 Y chromosomes on offensive attack may be mediated, at least in part, by differential effects of this Y chromosomal gene(s) on the sending and receiving of discriminable urinary odortypes. This hypothesis is based, in part, on the report that urine from a pair of Y chromosomal congenic strains (C57BL6.AKR-Y and C57BL6) of mice can be discriminated in a Y maze test. The AKR and C57BL6 Y chromosomes come from two distinct species of mouse (Mus domesticus andMus musculus, respectively). Thus, this Y chromosomal variant exists between mouse species. The DBA1 and C57BL10 Y chromosomes come from a single species,Mus musculus. Here we show that in the Y maze system previously used, urine from mice with the DBA1 and with the C57BL10 Y chromosomes can also be discriminated. Thus, there are discriminable urinary odortypes for this pair of Y chromosomes from the same species,Mus musculus.
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References
Bailey, D. W. (1978). Sources of subline divergence and their relative importance for sublines of six major inbred strains of mouse. In Morse, H. C. (ed.),Origins of Inbred Mice, Academic Press, New York, pp. 197–215.
Boyse, E. A., Beauchamp, G. K., Bard, J., and Yamazaki, K. (1991). Behavior and the major histocompatibility complex of the mouse. In Ader, R., Felten, D. L., and Cohen, N. (eds.),Psychoneuroimmunology, 2nd ed., Academic Press, New York, pp. 831–846.
Carlier, M., Roubertoux, P. L., Kottler, M. L., and Degrelle, H. (1990). Y chromosome and aggression in strains of laboratory mice.Behav. Genet. 20:137–156.
Carlier, M., Roubertoux, P. L., and Pastoret, C. (1991). The Y chromosome effect on intermale aggression in mice depends on the maternal environment.Genetics 129:231–236.
Jutley, J. K., and Stewart, A. D. (1985). Genetic analysis of the Y-chromosome of the mouse: Evidence for two loci affecting androgen metabolism.Genet. Res. Cambr. 47:29–34.
Lenington, S. (1991). The t complex: A story of genes, behavior, and populations.Adv. Study Behav. 20:51–86.
Maxson, S. C., Ginsburg, B. E., and Trattner, A. (1979). Interaction of Y-chromosomal and autosomal gene(s) in the development of intermale aggression.Behav. Genet. 9:219–226.
Maxson, S. C., Didier-Erickson, A., and Ogawa, S. (1989). The Y chromosome, social signals, and offense in mice.Behav. Neural Biol. 52:251–259.
McLaren A. (1987). Sex determination and H-Y antigen in mice. In Haseltine, F. P., McClure, M. E., and Goldberg, E. H. (eds.),Genetic Markers of Sex Determination, Plenum Press, New York, pp. 87–97.
Monahan, E. J. (1992).Y Chromosome, Chemosignals, and Agonistic Behavior of Mus musculus, Ph.D. dissertation, University of Connecticut, Storrs.
Monahan, E., and Maxson, S. C. (1990). Chemosignal dependent and independent effect of Y chromosomal gene(s) on offense in mice.Behav. Genet. 20:735.
Moutier, R., and Carlier, M. (1991). Mandible shape analysis in Y-congenic strains of mice.Lab. Anim. 25:303–307.
Müller, U., and Lattermann, U. (1988). H-Y antigens, testis differentiation, and spermatogenesis.Exp. Clin. Immunogenet. 5:176–185.
Nallaseth, F. S., and Dewey, M. J. (1986). Moderately repeated mouse Y chromosomal sequence families present distinct types of organization and evolutionary change.Nucl. Acid Res. 14:5295–5307.
Nishioka, Y. (1987). Y-chromosomal DNA polymorphism in mouse inbred strains.Genet. Res. Cambr. 50:69–72.
Novotny, M., Jemilo, B., and Harvey, S. (1990). Chemistry of rodent pheromones: molecular insights into chemical signaling in mammals. In MacDonald, D. W., Müller-Schwarze, D., and Natynczuk, S. E. (eds.),Chemical Signals in Vertebrates V, Oxford University Press, New York. pp. 1–22.
Schellinck, H. M., Monahan, E., Brown, R. E., and Maxson, S. C. (1993). A comparison of the contribution of the MHC and Y chromosomes to individual urine odors of mice.Behav. Genet. 23:257–263.
Scott, D., McLaren, A., Dyson, J., and Simpson, E. (1991). Variable spread of X inactivation affecting the expression of different epitopes of the Hya gene product in mouse B-cell clones.Immunogenetics 33:54–61.
Shrenker, P., and Maxson, S. C. (1986). Effect of the DBA/1Bg Y chromosome on testis weight and aggression.Behav. Genet. 16:263–270.
Stewart, A. D., Manning, A., and Batty, J. (1980). Effects of Y-chromosome variants on male behaviour of the mouse.Genet. Res. Cambr. 35:261–268.
van Abeelen, J. H. F., Leenders, H. J., and Lemmens, W. A. J. G. (1990). Y-chromosomal influences on renal and adrenal measures in mice.Growth Dev. Aging 54:151–154.
Wachtel, S. S. (1983).H-Y Antigen and Biology of Sex Determination, Grune & Stratton, New York.
Yamaguchi, M., Yamazaki, K., Beauchamp, G. K., Bard, J., Thomas, L., and Boyse, E. A. (1981). Distinctive urinary odors governed by the major histocompatibility locus of the mouse.Proc. Natl. Acad. Sci. 78:5817–5820.
Yamazaki, K., Yamaguchi, M., Beauchamp, G. K., Bard, J., Boyse, E. A., and Thomas, L. (1979). Recognition among mice: Evidence from the use of a Y-maze differentially scented by congenic mice of different major histocompatibility types.J. Exp. Med. 150:755–760.
Yamazaki, K., Beauchamp, G. K., Bard, J., Thomas, L., and Boyse, E. A. (1982). Chemosensory recognition of phenotypes determined by the Tla and H2K regions of chromosome 17 of the mouse.Proc. Natl. Acad. Sci. 79:7828–7831.
Yamazaki, K., Beauchamp, G. K., Bard, J., Thomas, L., and Boyse, E. A. (1983). Sensory distinction between H-2b and H-2bm1 mutant mice.Proc. Natl. Acad. Sci. 80:5685–5688.
Yamazaki, K., Beauchamp, G. K., Thomas, L., and Boyse, E. A. (1984). Chemosensory identity of H-2 heterozygotes.J. Cell. Mol. Immunol. 1:79–82.
Yamazaki, K., Beauchamp, G. K., Thomas, L., and Boyse, E. A. (1985). The hematopoietic system is a source of odorants that distinguish major histocompatibility types.J. Exp. Med. 162:1377–1380.
Yamazaki, K., Beauchamp, G. K., Matsuzaki, O., Bard, J., Thomas, L., and Boyse, E. A. (1986). Participation of murine X and Y chromosomes in genetically determined chemosensory identity.Proc. Natl. Acad. Sci. 83:4438–4440.
Yamazaki, K., Beauchamp, G. K., Bard, J., and Boyse, E. A. (1989). Sex-chromosomal odor types influence the maintenance of early pregnancy in mice.Proc. Natl. Acad. Sci. 86:9399–9401.
Yamazaki, K., Beauchamp, G. K., Imai, Y., Bard, J., Phelan, S. P., Thomas, L., and Boyse, E. A. (1990). Odortype determined by the major histocompatibility complex in germfree mice.Proc. Natl. Acad. Sci. 87:8413–8416.
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Monahan, E., Yamazaki, K., Beauchamp, G.K. et al. Olfactory discrimination of urinary odortypes from congenic strains (DBA/1Bg and DBA1.C57BL10-YBg) of mice differing in their Y chromosomes. Behav Genet 23, 251–255 (1993). https://doi.org/10.1007/BF01082463
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DOI: https://doi.org/10.1007/BF01082463