Abstract
A method has been developed to match corresponding heart regions from functional echocardiographic (Echo) and metabolic fluorine-l8-fluoro-2-deoxy-d-glucose ([18F]FDG) positron emission tomography (PET) studies in individual patients. Echo and PET images are spatially correlated by determining homologous anatomical landmarks (the two papillary muscles and the inferior junction of the right ventricle), identifiable in images obtained by both acquisition modalities. Echo-PET image registration is first performed in the plane identified by the three landmarks, using a rigid rotate-translate scale model. The registration parameters are then used to transform the whole PET volume. This allows a consistent Echo-PET regional analysis, according to a segmental subdivision of the heart. The technique was tested on patients. The overlay of Echo and PET registered images proved the reliability of realignment of the three markers and a good spatial correlation of myocardial walls. This approach to image registration could be applied to other acquisition modalities (such as magnetic resonance imaging and single-photon emission tomography), provided that the three anatomical landmarks are visualized.
This is a preview of subscription content, log in via an institution to check access.
References
Maisey MN, Hawkes DJ, Lukawiecki-Vydelingum AM. Synergistic imaging.Eur J Nucl Med 1992; 19: 1002–1005.
Smart SC, Sawada SG, Ryan T. Low dose dobutamine echocardiography detects reversible dysfunction after thrombolytic therapy of acute myocardial infarction.Circulation 1993; 88: 405–415.
Bonow RO, Dilsizian V, Cuocolo A, Bacharach SL. Myocardial viability in patients with chronic coronary artery disease and left ventricular dysfunction: thallium-201 reinjection versus18F-fluorodeoxyglucose.Circulation 1991; 83: 26–37.
Baer FM, Voth E, Deutsch HJ, Schneider CA, Schicha H, Sechtem U. Assessment of viable myocardium by dobutamine transesophageal echocardiography and comparison with fluorine-18 fluorodesoxyglucose positron emission tomography.J Am Coll Cardiol 1994; 24: 343–353.
Pierard LA, De Landsheere CM, Berthe C, Rigo P, Kullbertus HE. Identification of viable myocardium by echocardiography during dobutamine infusion in patients with myocardial infarction after thrombolytic therapy: comparison with positron emission tomography.J Am Coll Cardiol 1990; 15: 1021–1031.
Hawkes DJ, Hill DLG, Bracey EECML. Multi modal data fusion to combine anatomical and physiological information in the head and the heart. In: Reiber JHC, van Der Wall E, eds.Proceedings of the “International symposium of computing in nuclear medicine and cardiac MRI”. The Hague: Kluwer, 1991.
Levin DN, Pelizzari CA, Chen GTY, Chen CT, Cooper MD. Retrospective geometric correlation of MR, CT, and PET images.Radiology 1988; 169: 817–823.
Mann DL, Gillam LD, Wejman AE. Cross-sectional echocardiographic assessment of regional left ventricular performance and myocardial perfusion.Prog Cardiovasc Dis 1986; 25: 1–52.
Spinks TJ, Jones T, Gilardi MC, Heather JD. Physical performance of the latest generation of commercial positron scanner.IEEE Trans Nucl Sci 1988; NS-35: 721–725.
Rizzo G, Gilardi MC, Prinster A, Lucignani G, Bettinardi V, Triulzi F, Cardaioli A, Cerutti S, Fazio F. A bioimaging integration system (BIS) implemented for neurological applications.J Nucl Biol Med 1994; 38: In press.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Savi, A., Gilardi, M.C., Rizzo, G. et al. Spatial registration of echocardiographic and positron emission tomographic heart studies. Eur J Nucl Med 22, 243–247 (1995). https://doi.org/10.1007/BF01081520
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01081520