Abstract
Carcinoma of the pancreas and chronic pancreatitis may be extremely difficult to differentiate by standard diagnostic methods preoperatively as well as at the operating table. Operative pancreatic biopsy may have a high morbidity, rare mortality, and can be misleading. Percutaneous aspiration biopsy may be of great potential benefit. It provides additional histological material not usually available, and an accurate diagnosis of malignancy can be made. In select patients a needless laparotomy may be avoided. It appears to be a safe procedure that should be considered in the evaluation of the patient with suspected pancreatic malignancy in which a mass lesion is demonstrated by ultrasonography, computerized tomography, angiography, or retrograde pancreatography.
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References
Berg JW, Robbins GF: A late look at the safety of aspiration biopsy. Cancer 15:826–827, 1962
Bowden L: The fallibility of pancreatic biopsy. Ann Surg 139:403–408, 1954
Lightwood R, Reber HA, Way LW: The risk and accuracy of pancreatic biopsy. Am J Surg 132:189–194, 1976
Oscarson J, Stormby N, Sundgren R: Selective angiography in fine needle aspiration cytodiagnosis of gastric and pancreatic tumours. Acta Radiol 12:737–749, 1972
Anacker H: Efficiency and Limits of Radiologic Examination of the Pancreas. Massachusetts, Thieme-Edition/Publishing Sciences Group, Inc., 1975, pp 273–276
Hancke S, Holm HH, Koch F: Ultrasonically guided percutaneous fine needle biopsy of the pancreas. Surg Gynecol Obstet 140:361–364, 1975
Smith EH, Bartrum RJ, Jr, Chang YC, et al: Percutaneous aspiration biopsy of the pancreas under ultrasonic guidance. N Engl J Med 292:825–828, 1975
Tylen U, Arnesjo B, Lindberg LG, et al: Percutaneous biopsy of carcinoma of the pancreas guided by angiography. Surg Gynecol Obstet 142:737–739, 1976
Arnesjo B, Stormby N, Akerman M: Cytodiagnosis of pancreatic lesions by means of fine needle biopsy during operation. Acta Chir Scand 138:363–369, 1972
Schultz NJ, Sanders RJ: Evaluation of pancreatic biopsy. Ann Surg 158:1053–1057, 1963
Rosen PP: Histologic diagnosis of pancreatic disease (correspondence). N Engl J Med 293:97, 1975
Engzell U, Esposti PL, Rubo E, et al: Investigation of tumour spread in connection with aspiration biopsy. Acta Radiol 10:385–398, 1971
Franzen A, Zajicek J: Aspiration biopsy in diagnosis of palpable lesions of the breast. Acta Radiol 7:241–262, 1968
Kline TS, Neal HS: Needle biopsy—a pilot study. JAMA 224:1143–1146, 1973
Dreiling DA, Nieburgs HE, Janowitz HD: The combined secretin and cytology test in the diagnosis of pancreatic and biliary tract cancer: Med Clin North Am 44:801–815, 1960
Goldstein H, Ventzke LE: Value of exfoliative cytology in pancreatic carcinoma. Gut 9:316–318, 1968
Christofferson P, Poll P: Peroperative pancreas aspiration biopsies. Acta Pathol Microbiol Scand (Suppl) 212:28–32, 1970
Kline TS, Goldstein G, Neal HS: Pancreatic carcinoma, pancreatitis, and needle aspiration biopsy. Arch Surg 109:578–579, 1974
Forsgren L, Orell S: Aspiration cytology in carcinoma of the pancreas. Surgery 73:38–42, 1973
Shorey BA: Aspiration biopsy of carcinoma of the pancreas. Gut 16:645–647, 1975
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Goldman, M.L., Naib, Z.M., Galambos, J.T. et al. Preoperative diagnosis of pancreatic carcinoma by percutaneous aspiration biopsy. Digest Dis Sci 22, 1076–1082 (1977). https://doi.org/10.1007/BF01072861
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DOI: https://doi.org/10.1007/BF01072861