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Discrete colonic ulcers associated with oral contraceptives

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Summary

A case of focal colonic ulcerations is presented which probably was secondary to ischemic colitis induced by oral contraceptive use. In addition, the ulcerations were misinterpreted as mural rather than mucosal lesions because of the prominent local mucosal and submucosal edema. Benign ulcer should be considered in the differential diagnosis of focal colonic lesions, especially if the patient is a young female taking oral contraceptives.

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References

  1. Brennan MF, Clarke AM, MacBeth WA: Infarction of the midgut associated with oral contraceptives. N Engl J Med 279:1213–1214, 1968

    PubMed  Google Scholar 

  2. Kilpatrick Z, Silverman J, Betancourt E, Farman J, Lawson JT: Vascular occlusion of the colon and oral contraceptives —possible relation. N Engl J Med 278:438, 1968

    PubMed  Google Scholar 

  3. Reed D, Coon W: Thromboembolism in patients receiving progestional drugs. N Engl J Med 269:622–624, 1963

    PubMed  Google Scholar 

  4. Cotton PB, Thomas ML: Ischemic colitis and the contraceptive pill. Br Med J 3:27–28, 1971

    PubMed  Google Scholar 

  5. Hurwitz R, Martin A, Grossman B, Waddell W: Oral contraceptives and gastrointestinal disorders. Ann Surg 172:892–896, 1970

    PubMed  Google Scholar 

  6. Welin G, Persson T: Oral contraceptives and thrombosis of the coiliac artery. Lancet 2:1348, 1968

    Google Scholar 

  7. Civetta J, Colodney M: Mesenteric venous thrombosis associated with oral contraceptives. Gastroenterology 58:713–716, 1970

    PubMed  Google Scholar 

  8. Gelfand M: Ischemic colitis with a depot synthetic progestogen. Am J Dig Dis 178:275–277, 1972

    Google Scholar 

  9. Castelli MF, Qizilbash AH, Salem S, Fyshe TG: Ischemic bowel disease. Can Med Assoc J 111:935–941, 1974

    PubMed  Google Scholar 

  10. Cromar CDL: Benign ulcer of the cecum. Am J Dig Dis 13:230–232, 1946

    Google Scholar 

  11. Colizado EY, Fleshler B: Reversible vascular occlusion of the colon. Radiology 89:432–434, 1967

    PubMed  Google Scholar 

  12. Magilner AD: Solitary benign ulcer of the colon in childhood. Radiology 105:113–114, 1972

    PubMed  Google Scholar 

  13. Debenham GP: Ulcer of the cecum during oxyphenbutazone (tandearil) therapy. Can Med Assoc J 94:1182–1184, 1966

    PubMed  Google Scholar 

  14. Bravo AJ, Lowman RM: Benign ulcer of the sigmoid colon. Radiology 90:113–115, 1968

    PubMed  Google Scholar 

  15. Naiken VS, Rashman R: Giant ulcers of the transverse colon. JAMA 217:344, 1971

    PubMed  Google Scholar 

  16. Handin RI: Thromboembolic complications of pregnancy and oral contraceptives. Prog Cardiovas Dis 16:395–405, 1974

    Google Scholar 

  17. Goodrich SM, Wood JE: Peripheral venous distensibility and velocity of venous blood flow during pregnancy or oral contraceptives. Am J Obstet Gynecol 90:740, 1964

    PubMed  Google Scholar 

  18. Goodrich SM, Wood JE: Effects of estradiol 17 beta on peripheral venous distensibility and velocity of venous flow. Am J Obstet Gynecol 76:407, 1966

    Google Scholar 

  19. Wittenberg J, Athanasoulis CA, Williams L: Ischemic colitis: Radiology and pathophysiology. Am J Roentgenol 123:281–287, 1975

    Google Scholar 

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Bernardino, M.E., Lawson, T.L. Discrete colonic ulcers associated with oral contraceptives. Digest Dis Sci 21, 503–506 (1976). https://doi.org/10.1007/BF01072137

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  • DOI: https://doi.org/10.1007/BF01072137

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