Skip to main content
SpringerLink
Log in

Stress and the acute gastric mucosal lesion

  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Stremple JF, Mori H, Lev R, Jerzy Glass GB: The stress ulcer syndrome. Current Problems in Surgery (Monograph). Chicago, Publishers Year Book, Medical Publishers, Inc., April, 1973

    Google Scholar 

  2. Lucas CE, Sugawa C, Friend W, Walt AJ: Therapeutic implications of disturbed gastric physiology in patients with stress ulcerations. Am J Surg 123:25–34, 1972

    Google Scholar 

  3. Czaja AJ, McAlhany JC, Pruitt BA, Jr Acute gastroduodenal disease after thermal injury. N. Engl J Med 291:925–929, 1974

    Google Scholar 

  4. Watts CC, Clark K: Gastric acidity in the comatose patient. J Neurosurg 30:107–109, 1969

    Google Scholar 

  5. Norton L, Greer J, Eiseman B: Gastric secretory response to head injury. Arch Surg 101:200–204, 1970

    Google Scholar 

  6. Robbins R, Idjadi F, Stahl M, Essiet G: Studies of gastric secretion in stressed patients. Ann Surg 175:555–562, 1972

    Google Scholar 

  7. Skillman JJ, Gould SA, Chung RSD, et al: The gastric mucosal barrier: Clinical and experimental studies in critically ill and normal man, and in the rabbit. Ann Surg 172:564–584, 1970

    Google Scholar 

  8. Moody FG, Durbin RP: Effects of glycine and other instillates on concentration of gastric acid. Am J Physiol 209:122–126, 1955

    Google Scholar 

  9. Moody FG, Aldrete JS: Hydrogen permeability of canine gastric secretory epithelium during formation of acute superficial erosions. Surgery 70:154–160, 1971

    Google Scholar 

  10. Cheung L, Stephenson LW, Moody FG, Torma MJ, Zalewsky C: Direct effects of endotoxin on canine gastric mucosal permeability and histological changes. J Surg Res. To be published, April, 1975

  11. Harjola RT, Sivula A: Gastric ulceration following experimentally induced hypoxia and hemorrhagic shock: in vivo study of pathogenesis in rabbits. Ann Surg 163:21–28, 1966

    Google Scholar 

  12. Davenport HW, Barr LL: Failure of ischemia to break the dog's gastric mucosal barrier. Gastroenterology 65:619–624, 1973

    Google Scholar 

  13. Dorricott NJ, Eisenberg H, Silen W: Effect of intraarterial vasopressin on canine gastric mucosal permeability. Gastroenterology 65:625–629, 1973

    Google Scholar 

  14. Ritchie WP Jr: Effect of hemorrhage on electrical and pH gradients in the intact stomach of the subhuman primate. Gastroenterology 67:259–263, 1974

    Google Scholar 

  15. Ritchie WP Jr, Fisher RP: Studies on the pathogenesis of “stress ulcers”: Electrical potential difference and ionic fluxes across canine gastric mucosa during hemorrhagic shock. J Surg Res 3:173–179, 1972

    Google Scholar 

  16. Gerety DC, Guth PH: Restraint-induced gastric erosions: Role of acid back diffusion. Am J Dig Dis 17:1012–1018, 1972

    Google Scholar 

  17. Virchow R: Historisches kritisches und positives zure Lehre der Unterleib saffektionen. Virchow Arch Pathol Anat 5:281–375, 1853

    Google Scholar 

  18. Moody FG: Role of mucosal blood flow in the pathogenesis of gastric ulcers. I.E.P.T. Section 39A Volume 1, Chapter 10: Oxford and New York. Pergamon Press, 1973, pp 339–359

    Google Scholar 

  19. Menguy R, Desbaillets L, Masters YF: Mechanism of stress ulcer: Influence of hypovolemic shock on energy metabolism in the gastric mucosa. Gastroenterology 66:46–55, 1974

    Google Scholar 

  20. Watt J: The mechanisms of histamine ulceration in the guinea pig. Gastroenterology 37:741–759, 1959

    Google Scholar 

  21. Mersereau WA, Hinchey EF: Effect of gastric acidity on gastric ulceration induced by hemorrhage in the rat, utilizing a gastric chamber technique. Gastroenterology 64:1130–1135, 1973

    Google Scholar 

  22. Kristt DA, Freimark SJ: Histopathology and pathogenesis of behaviorally induced gastric lesions in rats. Am J Pathol 73:411–424, 1973

    Google Scholar 

  23. Freimark SJ: Effects of electrical stimulation of the brain on the formation of acute gastric lesions. Physiol Behav 11:855–858, 1973

    Google Scholar 

  24. Davis RA, Brooks FP: Experimental peptic ulcer associated with lesions or stimulation of the central nervous system. Surg Gynecol Obstet 116:307–320, 1963

    Google Scholar 

  25. Reed JD, Sanders DJ, Thorpe: Nerve stimulation on gastric acid secretion and mucosal blood flow in the anesthetized cat. J Physiol 214:1–13, 1971

    Google Scholar 

  26. Reed JD, Sanders DJ: Splanchnic nerve inhibition of gastric acid secretion and mucosal blood flow in anesthetized cats. J Physiol 219:555–570, 1971

    Google Scholar 

  27. Leonard AS, Long D, French LA, Peter ET, Wangensteen OH: Pendular pattern in gastric secretion and blood flow following phyothalmic stimulation—Origin of stress ulcer? Surgery 56:109–120, 1964

    Google Scholar 

  28. Byrne JJ: Current concepts: Shock. N Engl J Med 275:543–546, 1966

    Google Scholar 

  29. Kawaruda Y, Weiss R, Matsumoto T: Pathophysiology of stress ulcer: Pharmacologic doses of steroid. Am J Surg 129:249–254, 1975

    Google Scholar 

  30. Sethbhak S, Pfeiffer CJ, Roth JLA: Gastric mucosal ulceration following vasoactive agents: A new experimental model. Am J Dig Dis 15:261–270, 1970

    Google Scholar 

  31. Nicoloff DM, Peter ET, Leonard AS, Wangensteen OH: Catecholamines in ulcer provocation: Their possible role in stress ulcer formation. JAMA 191:11–113, 1965

    Google Scholar 

  32. Archibald LH, Moody FG, Simons M: Effect of isoproterenol on canine gastric acid secretions and blood flow. Surg Forum 25:409, 1974

    Google Scholar 

  33. Archibald LH, Moody FG, Simons M: Comparison of gastric mucosal blood flow determined by aminopyrine clearance and gamma-labeled microspheres. Accepted for publication, Gastroenterology.

  34. Archibald LH, Moody FG, Simons M: The measurement of gastric mucosal blood flow by radioactive microspheres. J Appl Physiol Accepted for publication, June, 1975

  35. Drapanas T, Woolworth WC, Reeder JW, et al.: Experiences with surgical management of acute gastric mucosal hemorrhage. Ann Surg 173:628–639, 1971

    Google Scholar 

  36. Guth PH, Hall P: Microcirculatory and mast cell changes in restraint induced gastric ulcer. Gastroenterology 50:562–570, 1966

    Google Scholar 

  37. Ritchie WP Jr, Breen JJ, Grigg DI: Prevention of stress ulcer by reducing gastric tissue histamine. Surgery 62:596–600, 1967

    Google Scholar 

  38. Tran TA, Gregg RV: Transmittal of restraint-induced gastric ulcers by parabiosis in rats. Gastroenterology 66:63–68, 1974

    Google Scholar 

  39. Brodie DA, Hanson HM: A study of the factors involved in the production of gastric ulcers by the restraint technique. Gastroenterology 38:353–360, 1960

    Google Scholar 

  40. DenBesten L, Hamza KN: Effect of bile salts on ionic permeability of canine gastric mucosa during experimental shock. Gastroenterology 62:417–424, 1972

    Google Scholar 

  41. Ritchie WP Jr: Acute mucosal damage increased by topical bile salts and mucosal ischemia. Surg Forum 25:416, 1974

    Google Scholar 

  42. Moody FG, Simons MA, Jackson T: The effect of p-chloromercuribenzene sulfonate on gastric parietal and surface cell function in the dog. Gastroenterology 68:279–284, 1975

    Google Scholar 

  43. Zalewsky CA, Moody FG, Simons MA: The effects of p-chloro-mercuribenzene sulfonate (PCMBS) upon ultrastructure of canine gastric surface cells. Gastroenterology, accepted for publication

  44. Lucas CE, Sugawa C, Riddle J, et al.: Natural history and surgical dilemma of “stress” bleeding. Arch Surg 102:266, 1971

    Google Scholar 

  45. Cheung LJ, Moody FG, Reese RS: Effect of aspirin, bile salt and ethanol on canine gastric mucosal blood flow, Surgery, June 1975

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, University of Utah School of Medicine, 84112, Salt Lake City, Utah

    Frank G. Moody MD, Laurence Y. Cheung MD, Margaret A. Simons MS & Charlotte Zalewsky MS

Authors
  1. Frank G. Moody MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Laurence Y. Cheung MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Margaret A. Simons MS
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Charlotte Zalewsky MS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moody, F.G., Cheung, L.Y., Simons, M.A. et al. Stress and the acute gastric mucosal lesion. Digest Dis Sci 21, 148–154 (1976). https://doi.org/10.1007/BF01072062

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01072062

Keywords

Search

Navigation