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High incidence of asymptomatic brain lesions in metastatic renal cell carcinoma

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Summary

The metastatic pattern of renal cell carcinoma has been well established. Studies have revealed a relatively high incidence of spread to lung, liver, bone and brain. A retrospective review of the records of ninety patients with metastatic renal cell carcinoma showed seven to have evidence of brain metastases. Six of the seven were asymptomatic at time of diagnosis. This study shows a significant incidence of asymptomatic brain metastases in patients with metastatic renal cell carcinoma. Subsequent to our chart review, an additional two patients have presented to our institution with asymptomatic brain lesions from metastatic renal cell carcinoma.

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Authors and Affiliations

  1. The J. Bentley Squier Urologic Clinic, Columbia-Presbyterian Medical Center, Department of Urology, College of Physicians and Surgeons, Columbia University, USA

    Eric K. Seaman & Ihor S. Sawczuk

  2. Joint Clinical Immunotherapy Program of Boston University School of Medicine and the New England Baptist Hospital and Cellcor Inc., 200 Wells Ave., 02159, Newton, MA, USA

    Susan Ross

Authors
  1. Eric K. Seaman
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  2. Susan Ross
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  3. Ihor S. Sawczuk
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Seaman, E.K., Ross, S. & Sawczuk, I.S. High incidence of asymptomatic brain lesions in metastatic renal cell carcinoma. J Neuro-Oncol 23, 253–256 (1995). https://doi.org/10.1007/BF01059958

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  • DOI: https://doi.org/10.1007/BF01059958

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