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Effects of mercuric chloride on the activities of brain enzymes in a fresh water teleost,Ophiocephalus (Channa) punctatus

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Abstract

The effects of an acute lethal (1.8 mg/L) and a sublethal concentration (0.3 mg/L) of mercuric chloride on the activities of alkaline phosphatase, acid phosphatase, glucose-6-phosphatase, Na+, K+ adenosine triphosphatase, succinic dehydrogenase, lactic dehydrogenase, pyruvic dehydrogenase and cholinesterase in the brain of a fresh water fish,Ophiocephalus (Channa) punctatus were determined. Exposures were for 4, 15 or 30 days. Acute exposure to mercuric chloride inhibited alkaline phosphatase activity while chronic treatment increased the activity. Acid phosphatase and Na+, K+ adenosine triphosphatase activities were elevated after four days, but chronic exposure inhibited their activities. The activities of glucose-6-phosphatase, succinic dehydrogenase, lactic dehydrogenase, pyruvic dehydrogenase, and cholinesterase were inhibited by both acute and chronic treatments. Maximum inhibitions occurred after four days with alkaline phosphatase and cholinesterase, 15 days with acid phosphatase and 30 days with glucose-6-phosphatase, Na+, K+ adenosine triphosphatase, and the three dehydrogenases.

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Sastry, K.V., Sharma, K. Effects of mercuric chloride on the activities of brain enzymes in a fresh water teleost,Ophiocephalus (Channa) punctatus . Arch. Environ. Contam. Toxicol. 9, 425–430 (1980). https://doi.org/10.1007/BF01055294

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  • DOI: https://doi.org/10.1007/BF01055294

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