Abstract
Literature data on inclusion compounds of psychotropic agents (hypno-sedative, anticonvulsive and antiepileptic drugs, neuroleptics and anxiolytics) with cyclodextrins and their derivatives are presented. Inclusion compounds of two novel psychotropic agents, gidazepam and cinazepam, withβ-cyclodextrin (1 : 1 and 1 : 2) were obtained. The structure of these complexes has been established by one- and two-dimensional1H-NMR (for solutions in DMSO) and IR (for solid state) spectroscopy.
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Andronati, S.A., Shapiro, Y.E., Yakubovskaya, L.N. et al. Inclusion compounds of psychotropic agents and cyclodextrins. J Incl Phenom Macrocycl Chem 24, 175–186 (1996). https://doi.org/10.1007/BF01053430
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DOI: https://doi.org/10.1007/BF01053430