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Data bank of three-dimensional structures of disaccharides, a tool to build 3-D structures of oligosaccharides

Part I. Oligo-mannose typeN-glycans

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Abstract

This work presents the first part of a database of conformations for all the disaccharide fragments that are found inN-glycans. The conformational study of the five disaccharides found in the oligo-mannose type are presented here. For each disaccharide, several possible conformations are described. A method is presented to obtain realistic models of oligosaccharides using molecular mechanic methods. Analysis of some possible conformations of the oligo-mannose type glycan Man6-GlcNAc2 is given as an illustration of the possibilities.

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Authors and Affiliations

  1. Laboratoire de Physicochimie des Macromolécules, INRA, BP 527, 44026, Nantes, Cedex 03, France

    Anne Imberty, Sophie Gerber, Vinh Tran & Serge Pérez

Authors
  1. Anne Imberty
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  2. Sophie Gerber
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  3. Vinh Tran
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  4. Serge Pérez
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On post-doctoral leave from CERMAV-CNRS, Grenoble, France

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Imberty, A., Gerber, S., Tran, V. et al. Data bank of three-dimensional structures of disaccharides, a tool to build 3-D structures of oligosaccharides. Glycoconjugate J 7, 27–54 (1990). https://doi.org/10.1007/BF01050401

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  • DOI: https://doi.org/10.1007/BF01050401

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