Abstract
The role of dormant B cells and cycles is analyzed in the context of a Lotka-Volterra network. It is shown that dormant B cells stabilize a cycle and that in this way both cooperate to preserve the internal image (memory) of an antigen. The network is embedded in a hierarchical scheme which allows adaptation, learning, and innovation by biased and random mutation.
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Behn, U., van Hemmen, J.L. Network description of the immune system: Dormant B cells stabilize cycles. J Stat Phys 56, 533–545 (1989). https://doi.org/10.1007/BF01044451
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DOI: https://doi.org/10.1007/BF01044451