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Extractive fermentation by Zymomonas mobilis and the use of solvent mixtures

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Summary

A systematic and comprehensive screening of 1330 solvents, individually and as mixtures, was undertaken with the aim of improving on present extractive fermentation technology. The screening resulted in the selection of a solvent mixture of 5% by volume 4-heptanone and 95% Adol 85 NF (primarily oleyl alcohol). The performance of this solvent mixture in an extractive fed-batch fermentation configuration was compared with that of pure Adol 85 NF. The solvent mixture had a distribution coefficient 12% higher than that of pure Adol 85 NF and had no significant inhibitory effect on the fermentation under typical operating conditions.

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Authors and Affiliations

  1. Department of Chemical Engineering, Queen's University, K7L 3N6, Kingston, Ontario, Canada

    L. J. Bruce & A. J. Daugulis

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  1. L. J. Bruce
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  2. A. J. Daugulis
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Bruce, L.J., Daugulis, A.J. Extractive fermentation by Zymomonas mobilis and the use of solvent mixtures. Biotechnol Lett 14, 71–76 (1992). https://doi.org/10.1007/BF01030917

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