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Lipase-mediated homotopic and heterotopic double resolutions of a planar chiral organometallic alcohol

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Summary

(±)-Tricarbonyl η6-3-methylbenzyl alcohol)chromium

was resolved to

of ∼100%e.e. and

of 92%e.e. by lipase-catalyzed transesterifications arranged in homotopic and heterotopic double resolutions.

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References

  • Blagg, J., Davies, S.G., Holman, N.J., Laughton, C.A., and Mobbs, B.E. (1986).J. Chem. Soc. Perkin Trans., 1, 1581–1589.

    Google Scholar 

  • Boaz, N.W. (1989).Tetrahedron Lett., 30, 2061–2064.

    Google Scholar 

  • Chen, C.-S. and Sih, C.J. (1989).Angew. Chem. Int. Ed. Engl., 28, 695–707.

    Google Scholar 

  • Drueckhammer, D.G., Barbas III, C.F., Nozaki, K., Wong, C.-H., Wood, C.Y., and Ciufolini, M.A. (1988).J. Org. Chem., 53, 1607–1611.

    Google Scholar 

  • Iwai, M. and Tsujisaka, Y. (1984). Fungal lipase. In: Lipases, B. Borgström and H. L. Brockman, eds., pp. 443–469, Amsterdam: Elsevier.

    Google Scholar 

  • Meyer, A. (1973).Ann. Chim. (Paris), 8, 397–404.

    Google Scholar 

  • Syldatk, C., Stoffregen, A., Brans, A., Fritsche, K., Andree, H., Wagner, F., Hengelsberg, H., Tafel, A., Wuttke, F., Zilch, H., and Tacke, R. (1988).Ann. N. Y. Acad. Sci., 542, 330–338.

    Google Scholar 

  • Wang, Y.-F., Lalonde, J.J., Momongan, M., Bergbreiter, D.E., and Wong, C.-H. (1988).J. Am. Chem. Soc., 110, 7200–7205.

    Google Scholar 

  • Yamazaki, Y. and Hosono, K. (1990a).Tetrahedron Lett., 31, 3895–3896.

    Google Scholar 

  • Yamazaki, Y. and Hosono, K. (1990b).Agric. Biol. Chem., 54, 3357–3361.

    Google Scholar 

  • Yamazaki, Y., Uebayasi, M., Someya, J., and Hosono, K. (1990c).Agric. Biol. Chem., 54, 1781–1789.

    Google Scholar 

  • Yamazaki, Y., Morohashi, N., and Hosono, K. (1991).J. Chromatogr., in press.

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Authors and Affiliations

  1. Fermentation Research Institute, AIST, 1-1-3 Higashi, 305, Tsukuba, Ibaraki, Japan

    Yoshimitsu Yamazaki & Kuniaki Hosono

  2. Tsukuba Research Laboratories, Toyo Ink MFG. Co., Ltd., 27-Wadai, 300-42, Tsukuba, Ibaraki, Japan

    Nobuo Morohashi

Authors
  1. Yoshimitsu Yamazaki
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  2. Nobuo Morohashi
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  3. Kuniaki Hosono
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Yamazaki, Y., Morohashi, N. & Hosono, K. Lipase-mediated homotopic and heterotopic double resolutions of a planar chiral organometallic alcohol. Biotechnol Lett 13, 81–86 (1991). https://doi.org/10.1007/BF01030455

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