Summary
The oxygen uptake rate of swine testicular cells grown on microcarriers is affected by glucose concentration. A higher uptake rate is observed when the glucose in the culture is depleted. The addition of glucose to the culture results in an immediate decrease in oxygen uptake. Removal of glucose results in an immediate return to the original rate.
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References
Fleischaker, R.J. (1982) Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Hu, W.S., Meier, J. and Wang, D.I.C. (1984) A mechanistic analysis of the inoculum requirement for the cultivation of mammalian cells on microcarriers. Biotechnol. Bioeng. (in press)
Zielke, H.R., Zielke, C.L. and Ozand, P.T. (1984) Fed. Proc., 43:121.
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Frame, K.K., Hu, WS. Oxygen uptake of mammalian cells in microcarrier culture—Response to changes in glucose concentration. Biotechnol Lett 7, 147–152 (1985). https://doi.org/10.1007/BF01027808
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DOI: https://doi.org/10.1007/BF01027808