Summary
A fluoroacetate/fluoropyruvate-sensitive mutant was derived from the parent strainCorynebacterium glutamicum ATCC 21513. Accumulation of various amino acids in the fermentation broth using the two strains was compared. The FA/FP-sensitive mutant accumulated about 26.5 g/L L-lysine and 2.2 g/L aspartic acid which was about 3-fold and 10-fold respectively, more than the amount produced by the parent strain.
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Costa-Ferreira, M., Duarte, J.C. Amino acid accumulation by an analogue sensitive mutant ofCorynebacterium glutamicum . Biotechnol Lett 14, 1025–1028 (1992). https://doi.org/10.1007/BF01021052
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DOI: https://doi.org/10.1007/BF01021052