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Die Beschreibung einer einfachen Filtrationstechnik zur Erfassung der Erythrozyten-Verformbarkeit in der Schwangerschaft

A simple filtration technique for the observation of the deformation of human erythrocytes during pregnancy

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Zusammenfassung

Mit Hilfe einer einfachen Apparatur, die von der rheologischen Arbeitsgruppe um Reid und Dormandy entwickelt wurde, untersuchten wir eine Gruppe gesunder schwangerer Frauen (n = 25) hinsichtlich der Filtrierbarkeit von Vollblut und einer 10%igen Erythrozytensuspension. Als Vergleich zogen wir eine Gruppe gesunder Nichtschwangerer (n = 7) unabhängig vom Ovarialzyklus heran. Wir fanden eine Reduktion der Fließrate bei den Schwangeren gegenüber dem Vergleichskolletiv.

Summary

A simple rheological test method, as developed by Reid and Dormandy, was applied. In a group of pregnant women (n = 25) without pathological conditions the filtrability of whole blood and of a 10% erythrocyte suspension was determined. The control is a group of healthy nonpregnant patients (n = 7) at different times of the ovulatory cycle. Compared with the control group the flow rate of whole blood in the pregnant state is decreased about 30 %, whereas that of the erythrocyte suspension about 40 %.

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Heilmann, L., Kurz, E. Die Beschreibung einer einfachen Filtrationstechnik zur Erfassung der Erythrozyten-Verformbarkeit in der Schwangerschaft. Blut 35, 213–221 (1977). https://doi.org/10.1007/BF00999462

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