Abstract
Taurine is in high concentration in the milk of most mammals. Intraperitoneal injection of [35S]taurine into lactating rats leads to the appearance of label in the milk, and the dpm/ml milk are significantly decreased by treatment with guanidinoethyl sulfonate (GES), an analog of taurine. Pups nursed by GES-treated mothers have retinal taurine levels about 45% lower than controls during the period from birth to 17 days old suggesting a dependence of retinal taurine on dietary intake during the neonatal period. These deficits in taurine may be associated with visual dysfunction as seen in adult rats depleted of retinal taurine.
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Lake, N. Taurine depletion of lactating rats: Effects on developing pups. Neurochem Res 8, 881–887 (1983). https://doi.org/10.1007/BF00964549
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DOI: https://doi.org/10.1007/BF00964549