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The clinician and the thyroid

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Abstract

The goiter prevalence in iodine-deficient regions is up to 25%–54%. The most frequent disease in these endemic areas is non-toxic goiter, which is, however, oftentimes connected with autonomously functioning thyroid tissue leading to borderline or overt hyperthyroidism. Other thyroid diseases like cancer, thyroiditis and hypothyroidism play only a minor role in a thyroid clinic, while cases of Graves' disease may be observed more frequently. The most cost-effective tools to evaluate thyroid patients are the hand, ear and mouth of the thyroid clinician. The differential diagnosis of thyroid disorders may be evaluated by a battery of diagnostic tools like in-vitro tests and high performance imaging modalities. Once the diagnosis is established, the appropriate therapeutic procedures (drugs, radioiodine, surgery) have to be chosen. This review should be considered as a guideline for the diagnosis and treatment of thyroid diseases. In addition, special problems concerning elderly patients and pregnant women are discussed, including the differential diagnosis of thyroid diseases.

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  1. Department of Nuclear Medicine, University of Bonn, Sigmund Freud Strasse 25, W-5300 Bonn 1, Federal Republic of Germany

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Biersack, H.J., Hotze, A. The clinician and the thyroid. Eur J Nucl Med 18, 761–778 (1991). https://doi.org/10.1007/BF00956719

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