Summary
We report transvaginal puncture of ectopic pregnancy and instillation therapy under sonographic control in 10 cases. Only patients with rising β-hCG levels were selected for treatment. In 9 cases we instilled methotrexate and in 1 case prostaglandin E2. A successful outcome was obtained in 8 patients, 7 had been treated with methotrexate and 1 with PG E2. Conservative treatment failed in two patients. However, these patients were already in the 10th respective 8th week of pregnancy. There were no side effects after methotrexate; the patient given PG E2 experienced severe discomfort, vomiting and cramps.
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Feichtinger W, Kemeter P (1987) Conservative treatment of ectopic pregnancy by transvaginal aspiration under sonographic control and methotrexate injection. Lancet I:381–382
Feichtinger W, Kemeter P (1986) Transvaginal sector scan sonography for needle guided transvaginal follicle aspiration and other applications in gynecologic routine and research. Fertil Steril 45:722–725
Kemeter P, Feichtinger W (1986) Trans-vaginal oocyte retrieval using a trans-vaginal sector scan probe combined with an automated puncture device. Human Reprod 1:21–24
Grant A (1962) The effect of ectopic pregnancy on fertility. Clin Obstet Gynecol 5:861–863
Tanaka T, Hayashi H, Kutsuzawa T, Fujimoto S, Ichinoe K (1982) Treatment of interstitial ectopic pregnancy with methotrexate: report of a successful case. Fertil Steril 37:851–852
Miyazaki Y, Shiina Y, Wake N, Okada Y, Yamazaki H, Takeda W, Ichinoe K (1983) Studies on non-surgical therapy of tubal pregnancy. Acta Obstet Gynaecol Jpn 35:489–497
Choriner HC (1985) Non-surgical management of ectopic pregnancy associated with severe hyperstimulation syndrome. Obstet Gynecol 66:740–743
Ory SJ (1986) Nonsurgical treatment of ectopic pregnancy. Fertil Steril 46:767–768
Ory SJ, Villanueva AL, Sand PK, Tamura RD (1986) Conservative treatment of ectopic pregnancy with methotrexate. Am J Obstet Gynecol 145:1299–1306
Rodi IA, Sauer MV, Gorrill MJ, Bustillo M, Cunning JE, Marshall JR, Buster JE (1986) The medical treatment of unruptured ectopic pregnancy with methotrexate and citrovorum rescue. Fertil Steril 46:811–813
Robertson DE, Smith W, Moye MA, Brinsden PR, Hansen JN, Lewis PM, Serhal P, Simonis EG, Craft IL (1987) Reduction of ectopic pregnancy by injection under ultrasound control. The Lancet I:974–975
Brandes MC, Young DD, Goldstein DP, Parmley TH (1986) Treatment of cornual pregnancy with methotrexate: Case report. Am J Obstet Gynecol 155:655–657
Higgins KA, Schwartz MB (1986) Treament of persistent trophoblastic tissue after salpingostomy with methotrexate. Fertil Steril 45:427–428
Van Thiel DH, Ross GT, Lipsett MB (1970) Pregnancies after chemotherapy of trophoblastic neoplasms. Science 169:1326–1331
Walden AM, Bagshawe KD (1979) Pregnancies after chemotherapy for gestational trophoblastic tumours. The Lancet II:1241
Lindblom B, Hahlin M, Källfelt B, Hamberger L (1987) Local prostaglandin F2α injection for termination of ectopic pregnancy. The Lancet I:776–777
Lundstrom V, Marsk L, Soderqvist G (1986) Treatment of early tubal pregnancies with a PGE2 analogue (sulpostrone). In: Soon TE, Ratnam SS, Min LS (eds) Handbook of Abstracts, 12th World Congress on Fertility and Sterility. Singapore, October 26–31, 1986
Robertson DE, Smith W, Craft I (1987) Reduction of ectopic pregancy by ultrasound methods. The Lancet II:1524
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Feichtinger, W., Kemeter, P. Treatment of unruptured ectopic pregnancy by needling of sac and injection of methotrexate or PG E2 under transvaginal sonography control. Arch Gynecol Obstet 246, 85–89 (1989). https://doi.org/10.1007/BF00934124
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DOI: https://doi.org/10.1007/BF00934124