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A removable ocular microdialysis system for measuring vitreous biogenic amines

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Abstract

A microdialysis system with a removable probe and a fixed scleral entry port is presented. The probe can be inserted several times with minimal trauma, permitting repeated sampling in one animal. The functioning of the setup is illustrated by the measurement of dopamine, dihydroxyphenyl acetic acid, and nordrenaline in the vitreous of healthy rabbits under physiological conditions.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Antwerp, Belgium

    Nicolaas Stempels & Marie-José Tassignon

  2. Department of Pharmaceutical Chemistry, Free University of Brussels, Belgium

    Sophie Sarre

Authors
  1. Nicolaas Stempels
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  2. Marie-José Tassignon
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  3. Sophie Sarre
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Stempels, N., Tassignon, MJ. & Sarre, S. A removable ocular microdialysis system for measuring vitreous biogenic amines. Graefe's Arch Clin Exp Ophthalmol 231, 651–655 (1993). https://doi.org/10.1007/BF00921960

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  • DOI: https://doi.org/10.1007/BF00921960

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