Abstract
Therapy for congenital glaucoma is primarily surgical. We have investigated 249 cases who have undergone trabeculectomy. There was a 79% success rate as regards to control of the IOP. Vision could be saved among the patients who had applied relatively early. At the end of the follow up which was 5 years IOP remained normal in the successful group. All the patients and their families were analysed genetically by their pedigrees and caryotypes. An autosomal recessive pattern with variable penetrance was found. The majority of the patients came from families with consanguineous marriages giving a rate of 66.6%. It was suggested that the course of the disease is highly affected by and related to parental consanguinity. An early age of onset and an accelerated clinical course could be well correlated.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Beauchamps GP, Parks M. Filtering surgery in children, barriers to success. Ophthalmology 1979; 86: 170–80.
Broughton WL, Parks M. An analysis of treatment of congenital glaucoma by goniotomy. Am J Ophthalmol 1981; 91: 566–72.
Burke JP, Bowell R. Primary trabeculotomy in congenital glaucoma. B J of Ophthalmol 1989; 73: 86–190.
Ermo F, Bonomi L. Trabeculectomy. Ophthalmologica 1975; 166: 311–20.
Hoskins HD, Kass MA, Becker-Shaffer. Diagnosis and therapy of the glaucomas, 6th edn. The CV. Mosb. Company, St. Louis. 1989: 605–23.
Kriegelstein GK. Congenital glaucoma. Diagnosis and management. Trans Ophthalmol Soc UK 1986; 195: 549–51.
Morgan KS, Black B, Ellis FD, Helveston EM. Treatment of congenital glaucoma. Am J of Ophthalmol 1981; 92: 799–803.
Rao KV, Sai CM, Balu BVN. Trabeculectomy in congenital glaucoma. Indian J Ophth 1984; 32: 439–40.
Turaçli ME. Konjenital glokomda trabekülektomi ameliyati. AÜ Tip Fak Göz Kli. Yil 1979; 30: 41–56.
Turaçli ME. Surgical treatment of congenital glaucoma. In: Hankind P, editor. 24th Congress of Ophthalmology. San Francisco, 1982 Acta, Part 1. Philadelphia in Lippincott Com 1984: 610–1.
Watson PG, Jakeman C. The complications of trabeculectomy. Eye 1990; 4: 425–38.
Hafez, Moustafa, Mohpel. Evidence of HLA linked susceptibility genes in primary congenital glaucoma. Egy Dis Mark 1990; 8(4): 191–7.
Dascotte JC, Asseman R, François P. et al. Traitement Chirurgical du Glaucome Congenital Resultats a Long Terme J Fra Opthal 1991; 14(4): 229–33.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Erol Turaçli, M., Gülderen Aktan, S., Şayli, B.S. et al. Therapeutical and genetical aspects of congenital glaucomas. Int Ophthalmol 16, 359–362 (1992). https://doi.org/10.1007/BF00917991
Issue Date:
DOI: https://doi.org/10.1007/BF00917991