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Lack of effect of nicotine on the fertility of male and female mice

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Summary

Nicotine, administered by sub-cutaneous injection over a period of six weeks, was found to be ineffective in breaking male mouse chromosomes as judged by dominant lethal tests. In addition, no indication of an effect of nicotine on the fertility of female mice, or on the development of the foetusin utero, was found.

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References

  • Bateman, A. J.: The partition of dominant lethals in the mouse between unimplanted eggs and deciduomata. Heredity (Lund)12, 467–475 (1958).

    Google Scholar 

  • Cattanach, B. M. andR. J. Edwards: The effects of triethylenemelamine on the fertility of male mice. Proc. roy. Soc. Edinb. B67, 54–64 (1958).

    Google Scholar 

  • Essenberg, J. M., L. Fagan andA. J. Malerstein: Chronic poisoning of the ovaries and testes of albino rats and mice by nicotine and cigarette smoke. West. J. Surg.59, 27–32 (1951).

    Google Scholar 

  • Grumbrecht, P., andA. Loeser: Nicotin und innere Sekretion. Erbpathologische Untersuchungen über Keimschädigungen durch Nicotin. Klin. Wschr.2, 853–858 (1941).

    Google Scholar 

  • Hotovy, R.: Versuche zur Frage des Einflusses der chronischen Nicotin-Schädigung auf Fruchtbarkeit und Nachkommenschaft. Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak.205, 54–56 (1948).

    Google Scholar 

  • Larson, P. S., H. B. Haag andH. Silvette: Tobacco. Experimental and Clinical Studies. Baltimore, USA: Williams & Wilkins Company 1961.

    Google Scholar 

  • Nice, L. B.: Comparative studies on the effects of alcohol, nicotine, tobacco smoke and caffeine on white mice. I. Effects on reproduction and growth. J. exp. Zool.12, 133–152 (1912).

    Google Scholar 

  • Thienes, C. H., C. F. Lombard, F. J. Fielding, A. J. Lesser, andM. J. Ellenhorn: Alterations in reproductive functions of white rats associated with daily exposure to nicotine. J. Pharmacol. exp. Ther.87, 1–10 (1946).

    Google Scholar 

  • Wilson, J. R.: The effect of nicotine on lactation in white mice. Amer. J. Obstet.43, 839–844 (1942).

    Google Scholar 

  • Yun, I. S., andY. S. Lee: Experimental studies on the relation between nicotine and sexual hormone. Folia Endocr. Japan11, 9–12 (1935).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Animal Genetics, Medical Research Council Mutagenesis Research Unit, West Mains Road, Edinburgh 9, Scotland

    Bruce M. Cattanach (Member M.R.C. Scientific Staff)

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  1. Bruce M. Cattanach
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Cattanach, B.M. Lack of effect of nicotine on the fertility of male and female mice. Zeitschrift für Vererbungslehre 93, 351–355 (1962). https://doi.org/10.1007/BF00888792

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  • DOI: https://doi.org/10.1007/BF00888792

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