Summary
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1.
X-rays in combination with urethane or mustard gas exhibit an additive effect as regards the formation of sex-linked recessive lethal mutations and chromosome breaks when applied toDrosophila melanogaster spermatozoa.
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2.
Their action in combination on the formation of translocations is synergistic.
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3.
The ends of chromosomes broken by X-rays, mustard gas, and urethane are as capable of rejoining with those produced by the same agent as the X-ray produced-ones are of rejoining with those produced by either mustard gas or urethane to form chromosomal disarrangements.
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Contribution No. 629.
This work was supported by a grant from the British Empire Cancer Campaign administered by Dr.Charlotte Auerbach.
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Oster, I.I. Interactions between ionizing radiation and chemical mutagens. Zeitschrift für indukt. Abstammungs- und Vererbungslehre 89, 1–6 (1958). https://doi.org/10.1007/BF00888496
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DOI: https://doi.org/10.1007/BF00888496