Skip to main content
Log in

Vitamin status of infants receiving long-term peritoneal dialysis

  • Brief Report
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract

The oral vitamin intakes and blood vitamin concentrations of seven infants receiving long-term peritoneal dialysis were measured. The serum concentrations of vitamin A, vitamin B12, vitamin C and folic acid were determined. Thiamine and riboflavin were assessed by the activation of erythrocyte transketolase and erythrocyte glutathione reductase, respectively. Vitamin B6 was measured as plasma pyridoxal phosphate. All patients received a daily vitamin supplement devoid of vitamin A. Dietary vitamin intake was derived from infant formula. In all cases, the patients' blood concentrations of the water-soluble vitamins were equal to or greater than normal infant values. Serum vitamin A levels were elevated despite the lack of supplementation. The combined dietary/supplemental water-soluble vitamin intake of the patients exceeded the recommended daily allowance in all but one patient. These preliminary data emphasize the need to further evaluate the vitamin requirements of infants receiving long-term peritoneal dialysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Makoff R (1991) Water-soluble vitamin status in patients with renal disease treated with hemodialysis or peritoneal dialysis. J Renal Nutr 1: 56–73

    Google Scholar 

  2. Blumberg A, Hanck A, Sander G (1983) Vitamin nutrition in patients on continous ambulatory peritoneal dialysis (CAPD). Clin Nephrol 20: 244–250

    PubMed  Google Scholar 

  3. Kriley M, Warady BA (1991) Vitamin status of pediatric patients receiving long-term peritoneal dialysis. Am J Clin Nutr 53: 1476–1479

    PubMed  Google Scholar 

  4. Warady BA, Kriley M, Lovell H, Farrell S, Hellerstein S (1988) Growth and development of infants with end-stage renal disése receiving long-term peritoneal dialysis. J Pediatr 112: 714–719

    PubMed  Google Scholar 

  5. Bayoumi RA, Rosalki SB (1976) Evaluation of methods of coenzyme activation of erythrocyte enzymes for detection of deficiency of vitamins B1, B2, and B6. Clin Chem 22: 327–335

    PubMed  Google Scholar 

  6. Nichoalds GE (1974) Assessment of status of riboflavin nutritive by assay of erythrocyte glutathione reductase activity. Clin Chem 20: 624–628

    PubMed  Google Scholar 

  7. National Research Council (1979) Recommended dietary allowances, 10th edn. National Academy Press, Washington, D. C.

    Google Scholar 

  8. Coleman JE, Watson AR (1992) Micronutrient supplementation in children on continuous cycling peritoneal dialysis (CCPD). Adv in Perit Dial Vol. 8: 396–401

    Google Scholar 

  9. Makoff R (1992) Vitamin supplement in patients with renal disease. Dial Transplant 21: 18–24

    Google Scholar 

  10. Stockberger RA, Parott KA, Alexander SR, Miller LT, Leklem JE, Jenkins RD (1987) Vitamin B6 status of children undergoing continuous ambulatory peritoneal dialysis. Nutr Res 7: 1021–1030

    Google Scholar 

  11. Paginini EP (1989) Overview of anemia associated with chronic renal disease: primary and secondary mechanisms. Semin Nephrol 9 [Suppl]: 3–8

    Google Scholar 

  12. Shah GM, Ross EA, Sabo A, Pichon M, Reynolds RD, Bhagavan H (1992) Effects of ascorbic acid and pyridoxine supplementation on oxalate metabolism in peritoneal dialysis patients. Am J Kidney Dis 20: 42–49

    PubMed  Google Scholar 

  13. Werb R, Clark WF, Lindsay RM, Jones EOP, Linton A (1979) Serum vitamin A levels and associated abnormalities in patients on regular dialysis treatment. Clin Nephrol 12: 63–68

    PubMed  Google Scholar 

  14. Greene HL (1993) Disorders of the water-soluble vitamin B-complex and vitamin C. Textbook of pediatric nutrition, 2nd edn. Raven Press, New York, pp 73–89

    Google Scholar 

  15. Goldsmith G (1961) Human requirement for vitamin C and its use in clinical medicine. Ann NY Acad Sci 92: 230–245

    PubMed  Google Scholar 

  16. Changbumrung S, Poshakrishana P, Vudhivai N, Hongtong K, Pongpaew P, Migasena P (1984) Measurements of B9, B2, B6 status in children and their mothers attending a well-baby clinic in Bangkok. Int J Vitam Nutr Res 54:149–159

    PubMed  Google Scholar 

  17. Andon MB, Reynolds RD, Moser-Veillon PB, Howard P (1989) Dietary intake of total and glycosylated vitamin B6 and the vitamin B6 nutritional status of unsupplemented lactating women and their infants. Am J Clin Nutr 50: 1050–1058

    PubMed  Google Scholar 

  18. Borschel MW, Kirksey A, Hannemann RE (1986) Effects of vitamin B6 intake on nutriture and growth of young infants. Am J Clin Nutr 43: 7–15

    PubMed  Google Scholar 

  19. Davis RE, Icke GC, Hilton JM, Orr E (1986) Serum thiamin, pyridoxal, cobalamin and folate concentrations in young infants. Acta Paediatr Scand 75: 402–407

    PubMed  Google Scholar 

  20. Smith AM, Picciano MF, Deering RH (1985) Folate intake and blood concentrations of term infants. Am J Clin Nutr 41 (3): 590–598

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Warady, B.A., Kriley, M., Alon, U. et al. Vitamin status of infants receiving long-term peritoneal dialysis. Pediatr Nephrol 8, 354–356 (1994). https://doi.org/10.1007/BF00866365

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00866365

Key words

Navigation