Abstract
Pyrazole derivatives were hydroxyalkylated at the C4 atom by hexafluoroacetate and methyl trifluoropyruvate. The products of the hydroxyalkylation were dehydrated to the corresponding alkylidene derivatives which were reacted with nucleophiles. Dicyanoethylenes, obtained from polyfluorocarbonyl compounds, alkylated pyrazol-5-ones with the formation of pyrazolopyran derivatives.
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A. N. Nesmeyanov Institute for Organometallic Compounds, Russian Academy of Sciences, 117813 Moscow. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 11, pp. 2617–2623, November, 1992.
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Golubev, A.S., Tyutin, V.Y., Chkanikov, N.D. et al. Reactions of highly electrophilic polyfluoro unsaturated compounds with pyrazole derivatives. Russ Chem Bull 41, 2068–2073 (1992). https://doi.org/10.1007/BF00863375
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DOI: https://doi.org/10.1007/BF00863375