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Acute renal failure after exercise in a child with renal hypouricaemia

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Abstract

We describe a 12-year-old boy with renal hypouricaemia who presented with acute renal failure after a 6-h sports training session. Back and loin pain were noted at presentation. Although serum creatinine and blood urea nitrogen were elevated, the serum uric acid concentration was normal (2.6 mg/dl). This decreased to 0.3 mg/dl after recovery. The pyrazinamide and probenecid tests revealed that the cause of renal hypouricaemia in this patient was totally defective uric acid reabsorption. Acute renal failure after exercise is a rare but serious complication in paediatric patients with renal hypouricaemia.

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Authors and Affiliations

  1. Department of Paediatrics, Faculty of Medicine, The University of Tokyo, Mejirodai Campus, 3-28-6 Mejirodai, 112, Bunkyo-ku, Tokyo, Japan

    Takashi Igarashi, Takashi Sekine, Hiroko Sugimura & Hiroshi Hayakawa

  2. Department of Paediatrics, Kikkoman General Hospital, Noda-city, Chiba, Japan

    Takashi Arayama

Authors
  1. Takashi Igarashi
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  2. Takashi Sekine
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  3. Hiroko Sugimura
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  4. Hiroshi Hayakawa
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  5. Takashi Arayama
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Igarashi, T., Sekine, T., Sugimura, H. et al. Acute renal failure after exercise in a child with renal hypouricaemia. Pediatr Nephrol 7, 292–293 (1993). https://doi.org/10.1007/BF00853226

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  • DOI: https://doi.org/10.1007/BF00853226

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