Summary
The responses of nine men and nine women to brief repetitive maximal exercise have been studied. The exercise involved a 6-s sprint on a non-motorised treadmill repeated 10 times with 30 s recovery between each sprint. The total work done during the ten sprints was 37,693±3,956 J by the men and 26,555±4,589 J by the women (M > F,P<0.01). This difference in performance was not associated with higher blood lactate concentrations in the men (13.96± 1.70 mmol·−1) than the women (13.09±3.04 mmol·l−1). An 18-fold increase in plasma adrenaline (AD) occurred with the peak concentration observed after five sprints. The peak AD concentration in the men was larger than that seen in the women (9.2 +- 7.3 and 3.7 ± 2.4 nmol · l−1 respectively,P<0.05). The maximum noradrenaline (NA) concentration occurred after ten sprints in the men (31.6±10.9 nmol·l−1) and after five sprints in the women (27.4 ± 20.8 nmol · l−1). Plasma cardiodilatin (CDN) and atrial natriuretic peptide (ANP) concentrations were elevated in response to the exercise. The peak ANP concentration occurred immediately postexercise and the response of the women (10.8 ± 4.5 pmol · l−1 was greater than that of the men (5.1 ± 2.6 pmol · l−1,P<0.05). The peak CDN concentrations were 163 ± 61 pmol · l−1 for the women and 135 ± 61 pmol · l−1 for the men. No increases in calcitonin gene related peptide (CGRP) were detected in response to the exercise. These results indicate differences between men and women in performance and hormonal responses. There was no evidence for a role of CGRP in the control of the cardiovascular system after brief intermittent maximal exercise.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Anderson JV, Bloom SR (1986) Atrial natriuretic peptide: what is the excitement all about? J Endocrinol 110:7–17
Anderson JV, Raine AGG, Poudler A, Bloom SR (1986) Effect of haemodialysis on plasma concentrations of atrial natriuretic peptide in adult patients with chronic renal failure. J Endocrinol 110:193–196
Bollerslev J, Svaregard J, Blaabjerg O, Pindburg T (1987) Atrial natriuretic peptide in relation to physical exercise. Scand J Clin Lab Invest 47:681–683
Brooks S, Burrin J, Cheetham ME, Hall GM, Yeo T, Williams C (1988) The responses of the catecholamines and β-endorphin to brief maximal exercise in man. Eur J Appl Physiol 57:230–234
Builder GE, Schofield TE, Blaine EH (1986) Release of atrial natriuretic factor. Effects of repetitive streatch and temperature. Am J Physiol 251:F817–821
Cheetham ME, Boobis LH, Brooks S, Williams C (1986) Human muscle metabolism during sprint running. J Appl Physiol 61:54–60
Davies CL, Kissinger PT, Shoup RE (1981) Strategies for the determination of serum or plasma norepinephrine by reverse phase liquid chromatography. Anal Chem 53:156–159
Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of blood, plasma and red cells in dehydration. J Appl Physiol 37:247–248
Edwards BS, Zimmerman RS, Schwab TR, Heinblein DM, Burnelt JC (1988) Atrial stretch, not pressure, is the principle determinant controlling the acute release of atrial natriuretic factor. Circ Res 62:191–195
Forssmann WG, Hock D, Lottspeich F, Henschen A, Kreye V, Christman M, Reinecke M, Metz J, Carlquist M, Mutt V (1983) The right auricle of the heart is an endocrine organ: cardiodilatin as a peptide hormone candidate. Anat Embryol 168:307–313
Jacobs I, Tesch PA, Bar-Or O, Karlsson J, Dotan R (1983) Lactate in human skeletal muscle after 10 and 30 s of supramaximal exercise. J Appl Physiol 55:365–367
Jezeová D, Vigas M, Tatár P, Kevtňanský R, Nazar K, Kaciuba-Uścilko H, Kozlowski S (1985) Plasma testosterone and catecholamine responses to physical exercise of different intensities in men. Eur J Appl Physiol 54:62–66
Lakomy HKA (1987) The use of a non-motorised treadmill for analysing sprint performance. Ergonomics 30:627–637
Maughan RJ (1982) A simple and rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20 μl blood sample. Clin Chim Acta 122:231–240
Meleagros L, Gibbs JSR, Ghatei MA, Bloom SR (1988) Increase in plasma cardiodilatin (amino-terminal pro-atrial natriuretic peptide) in cardiac failure and during recumbency. Br Heart J 60:39–44
Muldery PK, Ghatei MA, Bloom SR (1987) In vitro production and characterisation of low molecular weight forms of calcitonin gene-related peptide immunoreactivity from rat thyroid. Biochem Biophys Res Commun 144:883–890
Saito Y, Nakino K, Sugawira A, Nishimura K, Sakamoto M, Morit N, Yamada T, Itoh H, Shiono S, Kwimaya T, Hirai M, Ohi M, Ban T, Imwa H (1987) Atrial natriuretic peptide during exercise in healthy man. Acta Endocrinol 116:59–65
Sanchez J, Pequignot JM, Peyrin L, Monod H (1980) Sex differences in the sympatho-adrenal response to isometric exercise. Eur J Appl Physiol 45:147–154
Savard G, Strange S, Kiens B, Richter EA, Christensen NJ, Saltin B (1987) Noradrenaline spillover during exercise in active versus resting skeletal muscle in man. Acta Physiol Scand 131:507–515
Somers VK, Anderson JV, Conway J, Sleight P, Bloom SR (1986) Atrial natriuretic peptide is released by dynamic exercise in man. Horm Metab Res 18:871–872
Spriet LL, Ren JM, Hultman E (1988) Epinephrine infusion enhances muscle glycogenolysis during prolonged electrical stimulation. J Appl Physiol 64:1439–1444
Struthers AD, Brown MJ, Macdonald DWR, Beacham JL, Stevenson JC, Morris HR, MacIntyre I (1986) Human calcitonin gene related peptide: a potent endogenous vasodilator in man. Clin Sci 70:389–393
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Brooks, S., Nevill, M.E., Meleagros, L. et al. The hormonal responses to repetitive brief maximal exercise in humans. Europ. J. Appl. Physiol. 60, 144–148 (1990). https://doi.org/10.1007/BF00846035
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00846035