Abstract
College-age subjects with and without a parental history of hypertension completed a battery of tests of cognitive function on two separate occasions. Pulse rate and blood pressure were measured during performance of each task. In one session, subjects were told that their performance was being evaluated and videotaped from behind an observation mirror (Evaluation Condition). In the other session, subjects were told that their performance was not being observed (Nonevaluation Condition). Regardless of Evaluation Condition, Parental History subjects exhibited slower search of short-term memory than Non-Family History subjects during the first but not the second testing session. Parental History subjects displayed greater elevations in pulse rate than Nonparental History subjects during task performance. The results were interpreted as providing evidence that pathophysiological mechanisms associated with essential hypertension are not the only viable explanations of lower levels of cognitive performance exhibited by hypertensive subjects.
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Drummond, P. D. (1983). Cardiovascular reactivity in mild hypertension.J. Psychosom. Res. 27: 291–297.
Drummond, P. D. (1985). Cardiovascular reactivity in borderline hypertensives during behavioral and orthostatic stress.Psychophysiology 22: 621–628.
Elias, M. F., Robbins, M. A., and Schultz, N. R. (1987). Influence of essential hypertension on intellectual performance: Causation or speculation. In Elias, J, W., and Marshall, P. H. (eds.),Cardiovascular Disease and Behavior, Hemisphere, New York, pp. 107–149.
Elias, M. F., Schultz, N. R., Robbins, M. A., and Elias, P. K. (1989). A longitudinal study of neuropsychological performance by hypertensives and normotensives: A third measurement point.J. Gerontol. Psychol. Sci. 44: pp. 25–28.
Elias, M. F., Robbins, M. A., and Elias, P. K. (1991). Effects of cardiovascular disease and hypertension on cognitive behavior. In Baum, A., and Shapiro, A. P. (eds.),Foundations of Behavioral Medicine, Lawrence Erlbaum Associations, Hillsdale, NJ.
Falkner, B., Onesti, G., Angelakos, E. T., Fernandes, M., and Langman, C. (1979). Cardiovascular response to mental stress in normal adolescents with hypertensive parents.Hypertension 1: 23–30.
Franceschi, M., Tancredi, O., Smirne, S., Mercinelli, A., and Canal, A. (1982). Cognitive processes in hypertension.Hypertension 4: 226–229.
Goldman, H., Kleinman, K., Snow, M., Bidus, D., and Korol, B. (1974). Correlations of diastolic blood pressure and cognitive dysfunction in essential hypertension.Dis. Nerv. Syst. 35: 571–572.
Humphreys, M. S., and Revelle, W. (1984). Personality, motivation, and performance: A theory of the relationship between individual differences and information processing.Psychol. Rev. 91: 153–184.
Ito, N., Takeshita, A., Higuchi, S., and Nakamura, M. (1985). Venous abnormality in normotensive young men with a family history of hypertension.Hypertension 8: 142–146.
Jorgensen, R. S., and Houston, B. K. (1986). Family history of hypertension, personality patterns, and cardiovascular reactivity to stress.Psychosom. Med. 42: 102–117.
Levy, C. M., and Ransdell, S. E. (1989).Laboratory of Cognition and Perception, 2nd ed., Conduit, Iowa City.
Light, K. C. (1975). Slowing of response time in young and middle-aged hypertensive patients.Exp. Aging Res. 1: 209–227.
Light, K. C. (1978). Effects of mild cardiovascular and cerebrovascular disorders on serial reaction time performance.Exp. Aging Res. 4: 3–22.
Lorimer, A. R., Macfarlane, P. W., Provan, G., Duffy, T., and Lawrie, T. D. V. (1971). Blood pressure and catecholamine responses to “stress” in normotensive and hypertensive subjects.Cardiovasc. Res. 5: 169–173.
Madden, D. J., and Blumenthal, J. A. (1989). Slowing of memory-search performance in men with mild hypertension.Health Psychol. 8: 131–142.
Mancia, G., Gianfranco, P., Pomidossi, G., Grassi, G., Casaderi, R., and Zanchetti, A. (1987). Alerting reaction and rise in blood pressure during measurement by physician and nurse.Hypertension 9: 209–215.
Manuck, S. B., Proietti, J. M., Rader, S. J., and Polefrone, J. M. (1985). Parental hypertension, affect, and cardiovascular response to cognitive challenge.Psychosom. Med. 47: 189–200.
McCann, B. S., Shapiro, A. P., Whitley, B., Manuck., S. B. and Miller, R. E. (1990). Absence of behavioral differences in young normotensive adults as a function of parental history of hypertension.Am. J. Hypertens. 3: 225–229.
Reitan, R., and Davison, L. A. (1974).Clinical Neuropsychology, Current Status and Applications, John Wiley & Sons, New York.
Schultz, N. R., Elias, M. F., Robbins, M. A., Streeten, D. H. P., and Blakeman, N. (1989). A longitudinal study of the performance of hypertensive and normotensive subjects in the Weschler Adult Intelligence Scale.Psychol. Aging 4: 496–499.
Shapiro, A. P., Miller, R. E., King, H. E., Ginchereau, E. H., and Fitzgibbon, K. (1982). Behavioral consequences of mild hypertension.Hypertension 4: 355–360.
Spieth, W. (1965). Slowness of task performance and cardiovascular diseases. In Welford, A. T., and Birren, J. E. (eds.),Behavior, Aging, and the Nervous System, Charles C Thomas, Springfield, IL.
Steptoe, A., Melville, D., and Ross, A. (1984). Behavioral response demands, cardiovascular reactivity, and essential hypertension.Psychosom. Med. 46: 33–48.
Sternberg, S. (1969). The discovery of processing stages: Extensions of Donders' method.Acta Psychol. 30: 276–315.
Takeshita, A., Imaizumi, T., Ashihara, T., Yamamoto, K., Hoka, S., and Nakamura, M. (1982). Limited maximal vasodilator capacity of forearm resistance vessels in normotensive young men with a familial predisposition to hypertension.Circ. Res. 50: 671–677.
Toole, J. F. (1984).Cerebrovascular disorders, Raven Press, New York.
Waldstein, S. R., Ryan, C. M., Manuck, S. B., Parkinson, D. K., and Bromet, E. J. (1991). Learning and memory function in men with untreated blood pressure elevation.J. Consult. Clin. Psychol. 59: 513–517.
Weschler, D. (1981).WAIS-R Manual, Psychological Corp., New York.
Wilkie, F. L., and Eisdorfer, C. (1971). Intelligence and blood pressure in the aged.Science 172: 959–962.
Wilkie, F. L., Eisdorfer, C., and Nowlin, J. B. (1976). Memory and blood pressure in the aged.Exp. Aging Res. 2: 3–16.
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This research was supported in part by NIH Grant AG-03055 from the National Institute on Aging.
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Pierce, T.W., Elias, M.F. Cognitive function and cardiovascular responsivity in subjects with a parental history of hypertension. J Behav Med 16, 277–294 (1993). https://doi.org/10.1007/BF00844760
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DOI: https://doi.org/10.1007/BF00844760