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Effects of exercise with varying energy expenditure on high-density lipoprotein-cholesterol

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Abstract

To investigate the effect of varying energy expenditure on acute high-density lipoprotein-cholesterol (HDL-C) changes, 12 healthy endurance-trained men completed three- counterbalanced running trials at different energy expenditures: trial 1, 1690.3 (24.4) kJ [mean (SD)]; trial 2, 2529.1 (24.0) kJ; trial 3, 3384.3 (36.6) kJ, with exercise intensity at 75% of maximal oxygen consumption. For each trial, blood samples were collected at 24 h pre-exercise (24 h Pre), immediately post-exercise, 1 h post-exercise, 6 h post-exercise (6 h PE), and 24 h post-exercise (24 h PE). Plasma samples were analyzed for HDL-C, HDL2-C and HDL3-C subfractions, and triglycerides (TG). In addition, post-heparin plasma samples were analyzed at 24 h Pre, 6 h PE and 24 h PE for lipoprotein lipase activity (LPLA) and hepatic triglyceride lipase activity. All samples were corrected for plasma volume changes and compared to 24 h Pre (baseline). When trials were combined, an increase (P < 0.05) in HDL-C was observed 24 h PE, via an increase (P < 0.05) in HDL3-C. An increase (P < 0.05) in LPLA and decrease (P < 0.05) in TG at 24 h PE is suggested to be responsible for the increase in HDL3-C. In conclusion, no difference in HDL-C was observed among trials. However, when trials were combined, an increase in HDL-C was observed, suggesting that an energy expenditure of no greater than 3384 J is needed to promote favorable changes in HDL-C.

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Authors and Affiliations

  1. Human Energy Research Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    Paul S. Visich, Fredric L. Goss, Paul M. Gordon, Robert J. Robertson, Vijay Warty, Bart G. Denys & Kenneth F. Metz

  2. Central Michigan University, 112 Pearce Hall, 48859, Mt. Pleasant, MI, USA

    Paul S. Visich, Fredric L. Goss, Paul M. Gordon, Robert J. Robertson, Vijay Warty, Bart G. Denys & Kenneth F. Metz

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  1. Paul S. Visich
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  2. Fredric L. Goss
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  3. Paul M. Gordon
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  4. Robert J. Robertson
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  5. Vijay Warty
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  6. Bart G. Denys
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  7. Kenneth F. Metz
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Visich, P.S., Goss, F.L., Gordon, P.M. et al. Effects of exercise with varying energy expenditure on high-density lipoprotein-cholesterol. Europ. J. Appl. Physiol. 72, 242–248 (1996). https://doi.org/10.1007/BF00838646

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