Summary
Sodium and potassium urinary excretion were studied in rats irradiated with 700 r of x-rays. Na excretion was delayed and that of K increased during the first and third day after irradiation, causing a reduction in the Na/K ratio. No significant alteration in the concentration of these elements was noted in the blood plasma during the first few days after irradiation. Deoxycorticosterone acetate given to the rats after irradiation caused an even greater reduction in the Na/K ratio on the third day than did irradiation alone. Labeling with Na24 isotope confirmed that Na absorption from the intestine was delayed on the thrid and fourth days. Possibly disturbance of mineral corticoid adrenal function led to changes in mineral metabolism.
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Grodzenskii, D.É., Ivanenko, T.I. The effect of ionizing radiation on electrolyte metabolism in rats. Bull Exp Biol Med 51, 697–699 (1961). https://doi.org/10.1007/BF00833894
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DOI: https://doi.org/10.1007/BF00833894