Abstract
The reaction of 3-Phenyl-4-hydroxy-2-quinolones (1) and benzylammonium chloride yields the 4-aminocompounds2 as main products. The isoquinocondensed quinolones3 are formed as by-products. Thermolysis of 4-benzylamino-2-quinolones (4) affords also3. Better yields of3 are obtained by condensing the 4-aminoquinolones2 with benzaldehyde followed by thermal cyclodehydrogenation of the benzylidenamino compound6.
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Hern Prof. Dr.E. Ziegler zur Vollendung seines 70. Lebensjahres gewidmet.
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Stadlbauer, W., Kappe, T. Isochinolino[4,3-c]chinolone aus Phenylmalonylheterocyclen. Monatsh Chem 113, 751–760 (1982). https://doi.org/10.1007/BF00809016
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DOI: https://doi.org/10.1007/BF00809016