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Primary hypertrophic osteoarthropathy: Another heritable disorder associated with patent ductus arteriosus

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Summary

Patent ductus arteriosus (PDA) is a congenital malformation that has been linked to diverse heritable and chromosomal disorders. Primary hypertrophic osteoarthropathy (HOA) is a rare heritable syndrome in which digital clubbing and periostosis become evident without any underlying illness.

The objective of this article is to describe four patients with coexisting PDA and primary HOA. Surgical closure of the ductus showed no effect on the skeletal changes.

Primary HOA should be included among the heritable disorders that may be associated with PDA.

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Authors and Affiliations

  1. Rheumatology Service, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano #1, 14080, México, D.F., México

    Manuel Martínez-Lavín (Chief), Carlos Pineda, Carmen Navarro, Alfonso Buendía & Carlos Zabal

Authors
  1. Manuel Martínez-Lavín
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  2. Carlos Pineda
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  3. Carmen Navarro
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  4. Alfonso Buendía
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  5. Carlos Zabal
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Martínez-Lavín, M., Pineda, C., Navarro, C. et al. Primary hypertrophic osteoarthropathy: Another heritable disorder associated with patent ductus arteriosus. Pediatr Cardiol 14, 181–182 (1993). https://doi.org/10.1007/BF00795652

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  • DOI: https://doi.org/10.1007/BF00795652

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