Summary
Two pharyngeal hypophyses from patients with endocrine disorder were examined light microscopically and immunocytochemically. The pharyngeal hypophysis from a patient with primary hypothyroidism was hypertrophic, with TSH cell hyperplasia; while that from a patient treated with metoclopramide, a dopamine-receptor-blocking drug, showed PRL cell hyperplasia. These findings strongly suggest that under certain circumstances the pharyngeal hypophysis is able to respond with specific changes to variations in the endocrine feedback.
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Supported by the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) of Argentina
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Ciocca, D.R., Puy, L.A. & Stati, A.O. Immunocytochemical evidence for the ability of the human pharyngeal hypophysis to respond to change in endocrine feedback. Vichows Archiv A Pathol Anat 405, 497–502 (1985). https://doi.org/10.1007/BF00737175
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DOI: https://doi.org/10.1007/BF00737175