Summary
27 Patients following severe brain injury were studied with regard to metabolic alterations. Metabolic rate was calculated from measured RQ, respiratory minute volume and oxygen consumption, as soon as the patient was able to breathe spontaneously. Catabolism was defined by determination of N-balance. It was concluded that metabolism following cerebral injury is particularly enhanced compared to common trauma. The neurological course of patients, who after midbrain syndrome recovered in contrast to those who developed apallic syndrome had little influence on metabolic rates, however, it distinctly seemed to modify catabolism. Thus catabolism throughout the apallic phase was found to be higher. The requirements for a favourable recovery from severe brain injury were defined as a well balanced nitrogen regime apart from a high amount of carbohydrate and fat calories.
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Haider, W., Lackner, F., Schlick, W. et al. Metabolic changes in the course of severe acute Brain Damage. Europ. J. Intensive Care Med 1, 19–26 (1975). https://doi.org/10.1007/BF00735865
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DOI: https://doi.org/10.1007/BF00735865