Skip to main content
Log in

Effects of caffeine consumption on nicotine consumption

  • Human Pharmacology
  • Published:
Psychopharmacology Aims and scope Submit manuscript

Abstract

Coffee-drinking cigarette smokers take in more nicotine when they ingest almost no caffeine than when they ingest an amount of caffeine ranging from 75 mg to 300 mg. They do not take in relatively less nicotine as the dose of caffeine increases from 75 mg to 300 mg. It seems, then, that something due to caffeine deficit is responsible for the effect. Heavier users of caffeine show this effect less strongly than do lighter users of caffeine. These results are discussed in terms of the discriminability of caffeine and nicotine deficits and the possible influence of differential tolerance to caffeine. The importance of evaluating caffeine consumption when studying nicotine use and the importance of considering the chronic level of use of these drugs when studying their effects on behavior is indicated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • American Heart Association: How to stop smoking. (Pamphlet). 1969

  • Ashton, H., Watson, D. W.: Puffing frequency and nicotine intake in cigarette smokers. Brit. med. J.1970II, 679–681

  • Axelrod, J., Reichenthal, J.: The fate of caffeine in man and a method for its estimation in biological material. J. Pharmacol. exp. Ther.107, 519–523 (1953)

    Google Scholar 

  • Brecher, E. M.: Licit and illicit drugs. Boston: Little, Brown, 1972

    Google Scholar 

  • Charles, J. L., Stahr, H. M., Ikeda, R. M.: Automated determination of nicotine in total particulate matter of cigarette smoke. Tobacco Sci.13, 54–58 (1969)

    Google Scholar 

  • Colton, T., Gosselin, R. E., Smith, R. P.: The tolerance of coffee drinkers to caffeine. Clin. Pharmacol. Ther.9, 31–39 (1968)

    Google Scholar 

  • Frith, C. D.: The effect of varying the nicotine content of the cigarettes on human smoking behavior. Psychopharmacologia (Berl.)19, 188–192 (1971)

    Google Scholar 

  • Goldstein, A., Kaiser, S., Whitby, O.: Psychotropic effects of caffeine in man. IV. Quantitative and qualitative differences associated with habituation to coffee. Clin. Pharmacol. Ther.10, 489 (1969)

    Google Scholar 

  • Herman, C. P.: External and internal cues as determinants of the smoking behavior of light and heavy smokers. J Personal. Soc. Psychol.30, 664–672 (1974)

    Google Scholar 

  • Jarvik, M. E.: The role of nicotine in the smoking habit. In: Learning mechanisms in smoking. W. A. Hunt, ed., Chicago: Aldine 1970

    Google Scholar 

  • Jarvik, M. E., Glick, S. D., Nakamura, R. K.: Inhibition of cigarette smoking by orally administered nicotine. Clin. Pharmacol. Ther.11, 574–576 (1970)

    Google Scholar 

  • Kozlowski, L. T., Jarvik, M. E., Gritz, E. R.: Nicotine regulation and cigarette smoking. Clin. Pharmacol. Ther17, 93–97 (1975)

    Google Scholar 

  • Levi, L.: The effect of coffee on the function of the sympathoadreno-medullary system in man. Acta med. scand.181, 431–438 (1967)

    Google Scholar 

  • Lucchesi, B. R., Schuster, C. R., Emley, G. S.: The role of nicotine as a determinant of cigarette smoking frequency in man with observations of certain cardiovascular effects associated with the tobacco alkaloid. Clin. Pharmacol. Ther.8, 789–796 (1967)

    Google Scholar 

  • Ritchie, J. M.: The xanthines. In: The pharmacological basis of therapeutics, L. S. Goodman and A. Gilman eds., (4th ed.). New York: MacMillan 1970

    Google Scholar 

  • Russell, M. A. H.: Cigarette smoking: a natural history of a dependence disorder. Brit. J. med. Psychol.44, 9 (1971)

    Google Scholar 

  • Schubert, D. S. P.: Arousal seeking as a central factor in tobacco smoking among college students. Int. J. Soc. Psychiat.11, 221 (1965)

    Google Scholar 

  • Stripling, J. S., Alpern, H. P.: Nicotine and caffeine: disruption of the long-term store of memory and proactive facilitation of learning in mice. Psychopharmacologia (Berl.)38, 187–200 (1974)

    Google Scholar 

  • Thomas, C. B.: The relationship of smoking and habits of nervous tension. In: Smoking behavior: motives and incentives. W. Dunn, ed. Washington: V. H. Winston & Sons, 1973

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Presently at Department of Psychology, Wesleyan University, Middletown, Connecticut, U.S.A. 06457. This paper is based on a Dissertation submitted to Columbia University.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kozlowski, L.T. Effects of caffeine consumption on nicotine consumption. Psychopharmacology 47, 165–168 (1976). https://doi.org/10.1007/BF00735816

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00735816

Key words

Navigation