Abstract
Coffee-drinking cigarette smokers take in more nicotine when they ingest almost no caffeine than when they ingest an amount of caffeine ranging from 75 mg to 300 mg. They do not take in relatively less nicotine as the dose of caffeine increases from 75 mg to 300 mg. It seems, then, that something due to caffeine deficit is responsible for the effect. Heavier users of caffeine show this effect less strongly than do lighter users of caffeine. These results are discussed in terms of the discriminability of caffeine and nicotine deficits and the possible influence of differential tolerance to caffeine. The importance of evaluating caffeine consumption when studying nicotine use and the importance of considering the chronic level of use of these drugs when studying their effects on behavior is indicated.
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References
American Heart Association: How to stop smoking. (Pamphlet). 1969
Ashton, H., Watson, D. W.: Puffing frequency and nicotine intake in cigarette smokers. Brit. med. J.1970II, 679–681
Axelrod, J., Reichenthal, J.: The fate of caffeine in man and a method for its estimation in biological material. J. Pharmacol. exp. Ther.107, 519–523 (1953)
Brecher, E. M.: Licit and illicit drugs. Boston: Little, Brown, 1972
Charles, J. L., Stahr, H. M., Ikeda, R. M.: Automated determination of nicotine in total particulate matter of cigarette smoke. Tobacco Sci.13, 54–58 (1969)
Colton, T., Gosselin, R. E., Smith, R. P.: The tolerance of coffee drinkers to caffeine. Clin. Pharmacol. Ther.9, 31–39 (1968)
Frith, C. D.: The effect of varying the nicotine content of the cigarettes on human smoking behavior. Psychopharmacologia (Berl.)19, 188–192 (1971)
Goldstein, A., Kaiser, S., Whitby, O.: Psychotropic effects of caffeine in man. IV. Quantitative and qualitative differences associated with habituation to coffee. Clin. Pharmacol. Ther.10, 489 (1969)
Herman, C. P.: External and internal cues as determinants of the smoking behavior of light and heavy smokers. J Personal. Soc. Psychol.30, 664–672 (1974)
Jarvik, M. E.: The role of nicotine in the smoking habit. In: Learning mechanisms in smoking. W. A. Hunt, ed., Chicago: Aldine 1970
Jarvik, M. E., Glick, S. D., Nakamura, R. K.: Inhibition of cigarette smoking by orally administered nicotine. Clin. Pharmacol. Ther.11, 574–576 (1970)
Kozlowski, L. T., Jarvik, M. E., Gritz, E. R.: Nicotine regulation and cigarette smoking. Clin. Pharmacol. Ther17, 93–97 (1975)
Levi, L.: The effect of coffee on the function of the sympathoadreno-medullary system in man. Acta med. scand.181, 431–438 (1967)
Lucchesi, B. R., Schuster, C. R., Emley, G. S.: The role of nicotine as a determinant of cigarette smoking frequency in man with observations of certain cardiovascular effects associated with the tobacco alkaloid. Clin. Pharmacol. Ther.8, 789–796 (1967)
Ritchie, J. M.: The xanthines. In: The pharmacological basis of therapeutics, L. S. Goodman and A. Gilman eds., (4th ed.). New York: MacMillan 1970
Russell, M. A. H.: Cigarette smoking: a natural history of a dependence disorder. Brit. J. med. Psychol.44, 9 (1971)
Schubert, D. S. P.: Arousal seeking as a central factor in tobacco smoking among college students. Int. J. Soc. Psychiat.11, 221 (1965)
Stripling, J. S., Alpern, H. P.: Nicotine and caffeine: disruption of the long-term store of memory and proactive facilitation of learning in mice. Psychopharmacologia (Berl.)38, 187–200 (1974)
Thomas, C. B.: The relationship of smoking and habits of nervous tension. In: Smoking behavior: motives and incentives. W. Dunn, ed. Washington: V. H. Winston & Sons, 1973
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Presently at Department of Psychology, Wesleyan University, Middletown, Connecticut, U.S.A. 06457. This paper is based on a Dissertation submitted to Columbia University.
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Kozlowski, L.T. Effects of caffeine consumption on nicotine consumption. Psychopharmacology 47, 165–168 (1976). https://doi.org/10.1007/BF00735816
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DOI: https://doi.org/10.1007/BF00735816