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Subacute zinc deficiency in children with recurrent upper respiratory tract infection

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Abstract

Serum, urine and hair zinc levels in 20 patients with recurrent upper respiratory tract infection are compared with those of age- and sex-matched controls. Lower hair zinc (1.44 vs 2.00 mmol/g hair,P=0.004) and higher urinary zinc levels (2.2 vs 1.6 mmol/mol creatinine,P=0.05) were found, but no difference in serum zinc. The patients had lowernormal height for age (SD-score 0.2 vs 0.7,P=0.031), there was no difference in weight for height. No correlation was found between the zinc values and the duration of the complaints.

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References

  1. Recommended Dietary Allowances (1980) 9th edn. National Academy of Sciences, Washington, DC, 145

  2. Björkstén B, Bäck O, Gustavson KH, Hallmans, Hägglöf B, Tärnvik A (1980) Zinc and immune function in Down syndrome. Acta Paediatr Scand 69:183–187

    Google Scholar 

  3. Blazsek I, Mathé G (1984) Zinc and immunity. Biomed Pharmacother 38:187–193

    Google Scholar 

  4. Bondestam M, Foucard T, Gebre-Medhin M (1985) Subclinical trace element deficiency in children with undue susceptibility to infections. Acta Paediatr Scand 74:515–520

    Google Scholar 

  5. Chandra RK (1984) Excessive intake of zinc impairs immune responses. JAMA 252:1443–1446

    Google Scholar 

  6. De Groot HJ, De Haas EJM, D'Haese P, Heyndrickx A, De Wolff FA (1984) Determination by flameless atomic absorption of aluminum in serum and hair for toxicological monitoring of patients on chronic intermittent haemodialysis. Pharm Weekbl [Sci] 6:11–15

    Google Scholar 

  7. Harz AJ (1984) Overlap index. An alternative to sensitivity and specificity in comparing the utility of a laboratory test. Arch Pathol Lab Med 108:65–67

    Google Scholar 

  8. Henkin RI, Aamodt RL (1983) Redefinition of zinc deficiency. In: Inglett GE (ed) Nutritional bioavailability of zinc. American Chemical Society, Washington, DC, pp 83–107

    Google Scholar 

  9. Meadows N, Ruse W, Keeling PWN, Scopes JW, Thompson RPH (1983) Peripheral blood leucocyte zinc depletion in babies with intra-uterine growth retardation. Arch Dis Child 58:807–809

    Google Scholar 

  10. Simmer K, Thompson RPH (1985) Maternal zinc and intrauterine growth retardation. Clin Sci 68:395–399

    Google Scholar 

  11. Van den Hamer CJA, Cornelisse C, Hoogenraad TU, Van Wouwe JP (1985) Use of (69m) Zn loading test for monitoring zinc malabsorption. In: Mills CF, Bremner I, Chesters JK (eds) Trace elements in man and animals, Commonwealth Agricultural Bureaux, Slough UK, pp 689–691

  12. Van Wieringen JC, Roede MJ, Wit JM (1985) Groeidiagrammen voor patientenzorg. Tijdschr Kindergeneeskd 53:147–152

    Google Scholar 

  13. Van Wouwe JP, Van den Hamer CJA (1986) How to diagnose zinc deficiency? Pediatr Res 20:1034A

    Google Scholar 

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van Wouwe, J.P., van Gelderen, H.H. & Bos, J.H. Subacute zinc deficiency in children with recurrent upper respiratory tract infection. Eur J Pediatr 146, 293–295 (1987). https://doi.org/10.1007/BF00716478

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  • DOI: https://doi.org/10.1007/BF00716478

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