Summary
We believe this to be the third reported case of an unusual congenital sacral tumor-like lesion characterized histologically by the presence of dysplastic and immature renal-like tissue with a predominant glomerular and tubular structure.
This lesion appears important in the differential diagnosis of extrarenal nephroblastoma, and should be regarded as a dysplastic overgrowth.
An origin from mesonephric or metanephric remnants is suggested.
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References
Akhtar M, Kott E, Brooks B (1977) Extrarenal Wilms tumor. Report of a case and review of the literature. Cancer 40:3087–3091
Allan E (1975) Nephrogenic adenoma of the bladder. J Urol 113:35–41
Bernstein J (1974) The morphogenesis of renal parenchymal maldevelopment (Renal dysplasia). Ped Clin N Am 18:395–407
Bittencourt AL, Britto JF, Fonseca LE (1981) Wilms' tumor of the uterus. The first report of the literature. Cancer 47:2496–2499
Boccon-Gibod L, Petit J (1975) Le concept de dysplasie renal. A propos de 67 observations. Ann Anat Pathol 20:213–230
Burgess SB (1969) Supernumerary kidney. Report of a case. Arch Pathol 69:154–157
Cozzutto C, Lazzaroni-Fossati F (1980) Renal dysplasia with sacral perineal location. J Urol 124:901–903
Dehner L (1975) Pediatric Surgical Pathology. St Louis. The CV Mosby Company
Drake M, Franciosi RA, Spencer B, Baker T (1976) Ectopic renal tissue in the region of sacrum. A case report. Am J Pathol 182:8A (Abstract)
Ericsson NO, Ivemark EI (1958a) Renal dysplasia and pyelonephritis in infants and children. Part I Arch Pathol 66:255–263
Ericsson NO, Ivemark EI (1958b) Renal dysplasia and pyelonephritis in infants and children. Part II Primitive ductules and abnormal glomeruli. Arch Pathol 66:264–269
Goldman RL (1972) Nephrogenic metaplasia (nephrogenic adenoma, adenomatoid tumor) of the bladder. J Urol 108:565–567
Gonzales-Crussi F, Winkler RF, Mirkin DL (1978) Sacrococcygeal teratomas in infants and children. Relationship of histology to prognosis in 40 cases. Arch Pathol Lab Med 102:420–425
Greville Williams GE (1963) Renal angiomyolipoma with an epithelial component. J Pathol Bacteriol 86:223–225
Gruenwald P (1942) Tissue anomalies of probable neural crest origin in a twenty millimeter human embryo with myeloschisis. Arch Pathol 31:489–492
Kissane JM (1975) Pathology of Infancy and Childhood. The C.V. Mosby Company, St. Louis, p 582
Kissane JM (1974) Congenital malformations. In: Heptinstall R (ed) Pathology of the Kidney, 2th edi. Little Brown and Company, Boston, pp 63–117
Malik T, Malik G, Diesch G (1967) Retroperitoneal teratoma with nephroblastic tissue as the main component. Int Surg 47:246–249
Marsden HB, Lawler W (1982) Wilms' tumor and renal dysplasia: a hypothesis. J Clin Pathol 35:1069–1073
Milliser RV, Greenberg SR, Neiman BH (1969) Heterotopic renal tissue in the human adrenal gland. J Urol 192:280–284
Milliser RV, Greenberg SR, Neiman BH (1972) Heterotopic renal tissue in the human heart. J Urol 108:21–24
McCrory WW (1972) Developmental Nephrology. Cambridge Massachusetts, Harvard University Press
Nicholson GW (1934) Studies on tumor formation. Kidney in a teratoma. Guys Hosp Rep 84:140–156
Nogales FF, Ortega I, Rivera F, Armas JR (1980) Metanephrogenic tissue in immature ovarian teratoma. Am J Surg Pathol 4:297–299
Novak ER, Woodruff JD (1974) Novak's Gynecologic and Obstetric Pathology. WB Saunders Company, Philadelphia, London, Toronto, pp 321–322
O'Shea PA, Callaghan JF, Lawlor JB, Reddy VC (1981) “Nephrogenic adenoma”: an unusual metaplastic change of urothelium. J Urol 125:249–252
Risdon RA (1971) Renal dysplasia. J Clin Pathol 24:57–71
Schnoy N, Leistenschneider W (1982) Tumor of mesonephric origin in a diverticulum of the urethra. An ultrastructural study. Virchows Arch [Pathol Anat] 397:335–345
Sussman EB, Brice M, Gray GF (1974) Nephrogenic metaplasia of the bladder. J Urol 111:34–35
Thompson MR, Emmanueal IG, Campbell MS, Zachary RB (1973) Extrarenal Wilms tumor. J Ped Surg 8:37–41
Tokumitsu S, Tokumitsu K, Takeya M, Takeuchi T (1981) Developmentally heterotopic urogenital tissues in a retroperitoneal lipoma with hematopoiesis. Acta Pathol Jpn 31:289–297
Valdisserri Ro, Yunis EJ (1981) Sacrococcygeal teratomas: a review of 68 cases. Cancer 48:217–221
Vellios F, Garrett RA (1961) Congenital unilateral multicystic disease of the kidney. A clinical and anatomic study of seven cases. Am J Clin Pathol 35:244–254
Wade-Evans T, Langley FA (1961) Mesonephric tumors of the female genital tract. Cancer 14:711–725
Ward S, Dehner LP (1974) Sacrococcygeal teratoma with nephroblastoma. A variant of extra-gonadal teratoma in childhood. Cancer 33:1355–1363
Willis RA (1958) The Borderline of Embryology and Pathology. London Butterworth and Co, London TD, p 330
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Cozzutto, C., Stracca-Pansa, V. & Salano, F. Renal dysplasia of the sacral region: Metanephric dysplastic hamartoma of the sacral region. Vichows Archiv A Pathol Anat 402, 99–106 (1983). https://doi.org/10.1007/BF00695053
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DOI: https://doi.org/10.1007/BF00695053