Summary
Pharmacological doses of thyroxine are able to mimic the effects of long photoperiods in Japanese quail. In birds maintained on short daylengths thrice-weekly injections of 100 μg thyroxine cause full testicular maturation at rates not greatly different from those seen if quail are exposed to long days. Thyroxine stimulates increases in the secretion of FSH and LH, in pituitary prolactin content and in the hypothalamic content of Gn-RH. The effects are dose-dependent. If female quail kept on short daylengths are given thyroxine their ovaries develop and they lay eggs. In castrated male quail on short days thyroxine causes a ten-fold increase in circulating LH within a week. Thyroxine injections are also capable of maintaining quail in a photorefractory state even when they are transferred to short daylengths. The results suggest that thyroxine mimics long days by acting high in the photoneuroendocrine system and does not simply act to facilitate hormone secretion per se. This is in line with growing evidence in mammals and birds that parts of the photoperiodic machinery are sensitive to thyroid hormones.
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Abbreviations
- Gn-RH :
-
gonadotropin releasing hormone
- FSH :
-
follicle stimulating hormone
- LH :
-
luteinizing hormone
- T 4 :
-
thyroxine
References
Albers HE, Ferris CF, Leeman SE, Goldman BD (1984) Avian pancreatic polypeptide phase shifts hamster circadian rhythms when microinjected in the suprachiasmatic region. Science 223:833–835
Aron M, Benoit J (1934) Sur le conditionnement hormonique du développement testiculaire chez les oiseaux: rôle de la thyroîde. C R Soc Biol 116:218–220
Chakraborty S (1985) Investigations of the roles of prolactin and thyroid hormones in the phenomenon of photorefractoriness in European starlings and in two species of hamsters. PhD thesis, University of Bristol
Chaturvedi CM, Thapliyal JP (1980) Role of corticosterone and L-thyroxine in gonadal development of the common mynaAcridotheres tristis. Ind J Exp Biol 18:23–25
Davies DT, Bicknell RJ (1976) The effect of testosterone on the responsiveness of the quail's pituitary to luteinising hormone-releasing hormone (LH-RH) during photoperiodically induced testicular growth. Gen Comp Endocrinol 30:487–499
Dawson A, Goldsmith AR, Nicholls TJ (1985) Thyroidectomy results in termination of photorefractoriness in starlings (Sturnus vulgaris) kept in long daylengths. J Reprod Fertil 74:527–533
Earnest DJ, Turek FW (1985) Neurochemical basis for the photic control of circadian rhythms and seasonal reproductive cycles: role for acetylcholine. Proc Nat Acad Sci 82:4277–4281
Follett BK (1976) Plasma follicle-stimulating hormone during photoperiodically induced sexual maturation in male Japanese quail. J Endocrinol 69:117–126
Follett BK, Maung SL (1978) The rate of testicular maturation, in relation to gonadotrophin and testosterone levels, in quail exposed to various artificial photoperiods and to natural daylengths. J Endocrinol 78:267–280
Follett BK, Nicholls TJ (1984) Photorefractoriness in Japanese quail: possible involvement of the thyroid gland. J Exp Zool 232:573–580
Follett BK, Nicholls TJ (1985) Influences of thyroidectomy and thyroxine replacement on photoperiodically controlled reproduction in quail. J Endocrinol 107:211–221
Follett BK, Nicholls TJ (1988) Acute effect of thyroid hormones in mimicking photoperiodically induced release of gonadotropins in Japanese quail. J Comp Physiol B 157:837–843
Follett BK, Scanes CG, Cunningham FJ (1972) A radioimmunoassay for avian lutinizing hormone. J Endocrinol 52:359–378
Goldsmith AR, Hall M (1980) Prolactin concentrations in the pituitary gland and plasma of Japanese quail in relation to photoperiodically induced sexual maturation and egg laying. Gen Comp Endocrinol 42:449–454
Goldsmith AR, Nicholls TJ (1984a) Thyroidectomy prevents the development of photorefractoriness and the associated rise in plasma prolactin in starlings. Gen Comp Endocrinol 54:265–263
Goldsmith AR, Nicholls TJ (1984b) Thyroxine induces photorefractoriness and stimulates prolactin secretion in European starlings (Sturnus vulgaris). J Endocrinol 101:R1-R3
Goldsmith AR, Nicholls TJ, Plowman G (1985) Thyroxine treatment facilitates prolactin secretion and induces a state of photorefractorines in thyroidectomized starlings. J Endocrinol 104:99–103
Gupta, BBPd, Thapliyal JP (1984) Role of thyroid and testicular hormones in the regulation of basal metabolic rate, gonad development, and body weight of spotted munia,Lonchura punctulata. Gen Comp Endocrinol 56:66–69
Jaap RG (1933) Testis enlargement and thyroid administration in ducks. Poultry Sci 12:233–241
Kar A, Chandola A (1985) Seasonality in birds and reptiles: the involvement of thyroxine and tri-iodothyronine. In: Follett BK, Ishii S, Chandola A (eds) The endocrine system and the environment. JSPS, Tokyo and Springer, Berlin Heidelberg New York, pp 117–126
McNeilly AS, Etches RJ, Friesen HG (1978) A heterologous radioimmunoassay for avian prolactin: application to the measurement of prolactin in the turkey. Acta Endocrinol 89:60–69
Miller DS (1935) Effects of thyroxine on plumage of the English sparrows. J Exp Zool 71:293–309
Nicholls TJ, Goldsmith AR, Dawson A (1984) Photorefractoriness in European starlings: associated hypothalamic changes and the involvement of thyroid hromones and prolactin. J Exp Zool 232:567–572
Nicholls TJ, Goldsmith AR, Dawson A (1988) Photorefractoriness in birds and comparison with mammals. Physiol Rev (in press)
Oota Y, Nakashima H (1977) Replacement by ionophores of the photoperiodic light requirement inLemna gibba. G3. Plant Cell Physiol 18:1363–1367
Robinson JE, Follett BK (1982) Photoperiodism in Japanese quail: the termination of seasonal breeding by photorefractoriness. Proc R Soc London B 215:95–116
Thapliyal JP (1969) Thyroid in avian reproduction. Gen Comp Endocrinol [Suppl] 2:111–122
Thapliyal JP (1978) Reproduction in Indian birds. Pavo 16:191–201
Thapliyal JP, Garg RK (1969) Relation of thyroid to gonadal and body weight cycles in male weaver birds,Pleceus phillipinus. Arch Anat Histol Embryol 51:689–695
Thapliyal JP, Gupta BBPd (1984) Thyroid and annual gonad development, body weight, plumage pigmentation, and bill color cycles of Lal munia,Estrilda amandava. Gen Comp Endocrinol 55:20–28
Thapliyal JP, Garg RK, Pandha SK (1968) Effect of thyroxin on the gonad and body weight of spotted munia,Urolencha punctulata. J Exp Zool 169:279–286
Turek FN, Losee-Olson S (1986) A benzodiazepine used in the treatment of insomnia phase-shifts the mammalian circadian clock. Nature 321:167–168
Vaugien L (1954) Influence de l'obscuration temporaire sur la durée de la phase réfractaire du cycle sexuel du moineau domestique. Bull Biol Fr Belg 88:294–304
Wieselthier AS, van Tienhoven A (1972) The effect of thyroidectomy on testicular size and on the photorefractory period in the starling (Sturnus vulgaris). J Exp Zool 179:331–338
Zatz M, Brownstein MJ (1979) Intraventricular carbachol mimics the effects of light on the circadian rhythm in the rat pineal gland. Science 203:358–361
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Follett, B.K., Nicholls, T.J. & Mayes, C.R. Thyroxine can mimic photoperiodically induced gonadal growth in Japanese quail. J Comp Physiol B 157, 829–835 (1988). https://doi.org/10.1007/BF00691015
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DOI: https://doi.org/10.1007/BF00691015