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Papierchromatographische Fraktionierung der C17-Ketosteroide bei Ovarial-Insuffizienz und verschiedenen Formen der Maskulinisierung

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Literatur

  • Ahrens, D.: Studien über die Steroid- und Gonadotropinausscheidung beim „Idiopathischen“ Hirsutismus. Z. Vitamin-Hormon- u. Fermentforsoh.12, 15 (1961).

    Google Scholar 

  • Anton, H. U.: Beziehungen zwischen exogener Hormonzufuhr und endogenem Hormonstoffwechsel. Arch. Gynäk.193, 78 (1959).

    Google Scholar 

  • Axelrod, L. R., andJ. W. Goldzieher: The metabolism of 17α-hydroxyprogesterone and its relation to congenital adrenal hyperplasia. J. clin. Endocr.20, 238 (1960).

    Google Scholar 

  • — —: Enzymic inadequacies of human polycystic ovaries. Arch. Biochem.95, 547 (1961).

    Google Scholar 

  • Bahner, F., u.G. Schwarz: Congenitale Nebennierenrindenhyperplasie beim Mann mit normaler Keimdrüsenfunktion und Fertilität. Acta endocr. (Kbh.)38, 236 (1961).

    Google Scholar 

  • Baulieu, E. E., L. G. Huis in't Veld, A. Jaoudé etM. F. Jayle: Fractionnement et mesure des 17-cetosteroides urinaires neutres au cours de la maladie de Cushing. Acta endocr. (Kbh.)26, 153 (1957).

    Google Scholar 

  • Bierich, J. R.: Adrenogenitales Syndrom. In: Die Intersexualität vonCl. Overzier. Stuttgart: Georg Thieme 1961.

    Google Scholar 

  • Bongiovanni, A. M.: In vitro hydroxylation of steroids by whole adrenal homogenates of beef, normal man, and patients with the adrenogenital syndrome. J. clin. Invest.37, 1342 (1958).

    Google Scholar 

  • Bradlow, H. L., andT. F. Gallagher: Metabolism of 11β-hydroxy-Δ 4-androstene-3,17-dione in man. J. biol. Chem.229, 505 (1957).

    Google Scholar 

  • — —: Metabolism of 11β-hydroxy-Δ 4-androstene-3,17-dione in congenital adrenal hyperplasia. J. clin. Endocr.19, 1575 (1959).

    Google Scholar 

  • Brooks, R. V.: Disorders of biosynthesis in man. Brit. med. Bull.18, 148 (1962).

    Google Scholar 

  • Brown, J. B.: A chemical method for the determination of oestriol, oestrone and oestradiol in human urine. Biochem. J.60, 185 (1955).

    Google Scholar 

  • —,R. D. Bulbrook andF. C. Greenwood: An additional purification step for a method for estimating oestriol, oestrone and oestradiol-17β in human urine. J. Endocr.16, 49 (1957).

    Google Scholar 

  • Burstein, S., andR. I. Dorfman: Biosynthesis of C19-steroids from 4-14C-cholesterol and 7-3H-pregnenolone in vivo: Consideration of new pathways. Acta endocr. (Kbh.)40, 188 (1962).

    Google Scholar 

  • Butler, G. C., andG. F. Marrian: Chemical studies on adrenogenital syndrome. I. The isolation of 3α-hydroxyetiocholane-17-one, 3β-hydroxyetioallocholane-17-one (isoandrosterone), and an new triol from the urine of a woman with an adrenal hyperplasia. J. biol. Chem.124, 237 (1938).

    Google Scholar 

  • Chang, E., andT. L. Dao: Adrenal estrogens. I. Conversion of 4-C14-cortisone acetate to 11-oxygenated estrogens in women. J. clin. Endocr.21, 624 (1961).

    Google Scholar 

  • — —: Adrenal estrogens. II. Further characterizations of isolated urinary 11β-hydroxyestrone and 11β-hydroxyestradiol. Biochim. biophys. Acta (Amst.)57, 609 (1962).

    Google Scholar 

  • Clark, A. F., andS. Solomon: Influence of dehydroisoandrosterone on the in vivo conversion of 17α-hydroxypregnenolone to 17-ketosteroids. Fed. Proc.21, 189 D (1962).

    Google Scholar 

  • Corker, C. S., J. K. Norymberski andR. Thow: Some aspects of the Zimmermann-reaction. Biochem. J.83, 583 (1962).

    Google Scholar 

  • Diczfalusy, E., andO. Cassmer: Urinary 17-ketosteroids following administration of long acting testosterone esters. J. clin. Endocr.21, 271 (1961).

    Google Scholar 

  • Dorfman, R. I.: InL. I. Gardner (Ed.), Symposium on adrenal function in infants and children, S. 66. Syracuse (N.Y.): Public Relations Officer, State University of New York, Upstate Medical Center 1954.

    Google Scholar 

  • —, andF. Ungar: Metabolism of steroid hormones. Minneapolis 15: Burges Publishing Co. 1954.

    Google Scholar 

  • Dyrenfurth, J., O. J. Lucis, J. C. Beck andH. Venning: Studies in patients with adrenocortical hyperfunction. III. In vitro secretion of steroids by human adrenal glands. J. clin. Endocr.20, 765 (1960).

    Google Scholar 

  • Eberlein, W. R., andA. M. Bongiovanni: Pathophysiology of congenital adrenal hyperplasia. Metabolism9, 326 (1960).

    Google Scholar 

  • Erez, N., andE. Yenen: A case of adrenogenital syndrome (adrenal pseudohermaphroditism) with subsequent pregnancy. Amer. J. Obstet. Gynec.76, 877 (1958).

    Google Scholar 

  • Forestier, B.: Contribution à l'étude du bilan steroide dans l'hirsutisme de la femme. Thèse Doct. Med. Lyon 1960.

  • Fukushima, D. K., H. L. Bradlow, L. Hellman, B. Zumoff andT. F. Gallagher: Study of 17-hydroxyprogesterone-4-C14 in man. J. clin. Endocr.21, 765 (1961).

    Google Scholar 

  • Gallagher, T. F.: Experimental studies of adrenal hyperfunction in man. Proc. 4. Internat. Congr. Biochem., Bd. IV. London: Pergamon Press 1959.

    Google Scholar 

  • —,A. Kappas, L. Hellman, M. B. Lipsett, O. H. Pearson andC. D. West: Adrenocortical hyperfunction in “idiopathic” hirsutism and Stein-Leventhalsyndrome. J. clin. Invest.37, 794 (1958).

    Google Scholar 

  • Gans, F., andJ. Ser: Normal pregnancy and delivery in female pseudohermaphroditism. Acta endocr. (Kbh.)30, 424 (1959).

    Google Scholar 

  • Gemzell, C. A., K.-G. Tillinger andA. Westman: Hirsutism. Acta endocr. (Kbh.)30, 387 (1959).

    Google Scholar 

  • German, E., H. Horowitz, R. van de Wiele andR. M. Torack: Leydig-cell tumor of the ovary: Case report and review. J. clin. Endocr.21, 91 (1961).

    Google Scholar 

  • Gibson, G., andJ. K. Norymberski: A note on the rapid assay of 17-ketogenic steroids in urine. Ann. rheum. Dis.13, 59 (1954).

    Google Scholar 

  • Göbel, P., F. Heni u.L. Ulrich: Über die Schwefelsäure-Alkohol-Reaktion von Dehydroepiandrosteron und ihre klinische Bedeutung. Endokrinologie37, 65 (1959).

    Google Scholar 

  • Grant, J. K.: Studies on the biogenesis of the adrenal steroids. Brit. med. Bull.18, 99 (1962).

    Google Scholar 

  • Heni, F., u.P. Göbel: Familiärer postpuberaler Hirsutismus. Endokrinologie37, 230 (1959).

    Google Scholar 

  • Herrmann, W. L.: Die Bestimmung von 17-Ketosteroidestern im Blut. Gynaecologia (Basel)151, 156 (1961).

    Google Scholar 

  • —,F. Buckner andJ. McL. Morris: The problem of “mild” adrenal hyperplasia. Fertil. and Steril.11, 74 (1960).

    Google Scholar 

  • Huis in't Veld, L. G.: The neutral 17-ketosteroid excretion during the menstrual cycle. Acta endocr. (Kbh,)33, 494 (1960).

    Google Scholar 

  • Ingersoll, F. M., andJ. W. McArthur: Longitudinal studies of gonadotropin excretion in Stein-Leventhal-syndrome. Amer. J. Obstet. Gynec.77, 795 (1959).

    Google Scholar 

  • Jacobsohn, G. M., andS. Lieberman: Studies in the chemical cleavage of the urinary glucuronosides of the 17-ketosteroids. J. biol. chem.237, 1469 (1962).

    Google Scholar 

  • Jailer, J. W.: Virilism. Bull. N.Y. Acad. Med.29, 377 (1953).

    Google Scholar 

  • —,J. J. Gold, R. L. van de Wiele andS. Lieberman: 17α-hydroxyprogesterone and 21-desoxyhydrocortisone; their metabolism and possible role in congenital adrenal virilism. J. clin. Invest.34, 1639 (1955).

    Google Scholar 

  • —, andR. L. van de Wiele: Studies in hirsutism. Urinary excretion of neutral 17-ketosteroids. Gynaecologia (Basel)138, 276 (1954).

    Google Scholar 

  • James, V. H. T.: The excretion of individual 17-oxosteroids in cushings syndrome. J. Endocr.23, 119 (1961).

    Google Scholar 

  • Jayle, M. F., L. G. Huis in't Veld, E. Baulieu etO. Crèpy: Contribution a l'étude du métabolisme et du dosage de la 3β-hydroxyandrostane-17-one (epiandrosterone) chez l'homme. Acta endocr. (Kbh.)21, 115 (1956).

    Google Scholar 

  • —,R. Scholler, P. Mauvais-Jarvis etS. Mètay: Excretion des steroids chez des femmes presentant un virilisme pilaire associe a des troubles du cycle menstruel. Acta endocr. (Kbh.)36, 375 (1961).

    Google Scholar 

  • Jefferies, W. McK., andR. P. Levy: Treatment of ovarian dysfunction with small doses of cortisone or hydrocortisone. J. clin. Endocr.19, 1069 (1959).

    Google Scholar 

  • —, andA. M. Michelakis: Studies of individual patterns of urinary 17-ketosteroid fractions. J. Lab. clin. Med.58, 831 (1961).

    Google Scholar 

  • Johnsen, S. G.: Fractionation of urinary 17-ketosteroids. III. The clinical significance of the simplified fractionated 17-ketosteroid determination. Acta endocr. (Kbh.)21, 157 (1956).

    Google Scholar 

  • Kallio, H.: Medullary resection of the ovaries in treatment of the Stein-Leventhal-syndrome: Report of 11 cases. Acta obst. gynec. scand.40, 16 (1961).

    Google Scholar 

  • Kappas, A., O. H. Pearson, C. D. West andT. F. Gallagher: A study of “idiopathic” hirsutism; a transitional adrenal abnormality. J. clin. Endocr.16, 517 (1956).

    Google Scholar 

  • Karl, H. J.: Die Funktion der Nebennierenrinde bei Frauen mit Hirsutismus und Cyclusstörungen. Klin. Wschr.38, 634 (1960).

    Google Scholar 

  • Kase, N., E. Forchielli andR. I. Dorfman: In vitro production of testosterone and androst-4-ene-3,17-dione in a human ovarian homogenate. Acta endocr. (Kbh.)37, 19 (1961).

    Google Scholar 

  • Kecskés, L., F. Mutschler, E. Thán u.I. Farkas: Papierchromatographische Isolation des Oestrons, 17β-Oestradiols und Oestriols aus menschlichen Ovarien. Acta endocr. (Kbh.)39, 483 (1962).

    Google Scholar 

  • Keettel, W. C., J. T. Bradbury andF. J. Stoddard: Observations on the polycystic ovary syndrome. Amer. J. Obstet. Gynec.73, 954 (1957).

    Google Scholar 

  • Keller, M., u.A. Hauser: Der klinische Wert der chromatographischen Fraktionierung der neutralen 17-Ketosteroide in der Gynäkologie. Arch. Gynäk.190, 241 (1958).

    Google Scholar 

  • — — andA. Walser: Virilizing adrenal adenoma associated with increased urinary excretion of estrogens and 17-ketosteroids. Isolation of steroids from the tumor. J. clin. Endocr.18, 1384 (1958).

    Google Scholar 

  • Klinefelter jr.,H. F., F. Albright andG. C. Griswold: Experience with a quantitative test for normale or decreased amounts of follicle stimulating hormone in the urine in endocrinological diagnosis. J. clin. Endocr.3, 529 (1943).

    Google Scholar 

  • Klopper, A.: Some observations on the sulphuric acid colour reaction for the estimation of pregnanediol. J. Endocr.13, 291 (1956).

    Google Scholar 

  • —,E. A. Michie andJ. B. Brown: A method for the determination of urinary pregnanediol. J. Endocr.12, 209 (1955).

    Google Scholar 

  • Knuppen, R., andH. Breuer: Biogenesis of 11β-hydroxyoestrone and 16α-hydroxyoestrone by adrenal tissue. Biochim. biophys. Acta (Amst.)58, 147 (1962).

    Google Scholar 

  • Kovacic, N., J. Matovinovic andM. Prosenjak: Qualitative differences in urinary 17-ketosteroid excretion in patients with Cushing's syndrome, Acta endocr. (Kbh.)24, 393 (1957).

    Google Scholar 

  • Labhart, A.: Klinik der inneren Sekretion. Berlin-Göttingen-Heidelberg: Springer 1957.

    Google Scholar 

  • Lanthier, A.: Urinary 17-ketosteroids in the syndrome of polycystic ovaries and hyperthecosis. J. clin. Endocr.20, 1587 (1960).

    Google Scholar 

  • —,S. Lauze andC. E. Grignon: The syndrome of polycystic ovaries and hyperthecosis. A clinical evaluation. Amer. J. med. Sci.239, 585 (1960).

    Google Scholar 

  • —, andT. Sandor: “In vitro” production of androgenic steroids by human normal and Stein Leventhal type ovarian slices. Metabolism9, 861 (1960).

    Google Scholar 

  • — —: The in vitro biosynthesis of androgenic steroids by human normal and “Stein Leventhal type” ovarian slices. Acta endocr. (Kbh.)39, 145 (1962).

    Google Scholar 

  • Leon, N., M. Nevese Castro andR. I. Dorfman: Biosynthesis of testosterone by a Stein-Leventhal ovary. Acta endocr. (Kbh.)39, 411 (1962).

    Google Scholar 

  • Leventhal, M. L.: The Stein-Leventhal-syndrome. Amer. J. Obstet. Gynec.76, 825 (1958).

    Google Scholar 

  • Lipsett, M. B.: Precursors of etiocholanolone and androsterone in adrenal carcinoma. Proc. Soc. exp. Biol. (N.Y.)107, 439 (1961).

    Google Scholar 

  • —, andB. D. Riter: Urinary ketosteroids and pregnanetriol in hirsutism. J. clin. Endocr.20, 180 (1960).

    Google Scholar 

  • — —: Urinary steroids in post-natal adrenal hyperplasia with virilism. Acta endocr. (Kbh.)38, 481 (1961).

    Google Scholar 

  • Lombardo, M. E., C. McMorris andP. B. Hudson: The isolation of steroidal substances from human adrenal vein blood. Endocrinology65, 426 (1959).

    Google Scholar 

  • Loraine, J. A.: Recent work on the quantitative determination of pituitary gonadotrophins in urine. Acta endocr. (Kbh.), Suppl.31, 75 (1957).

    Google Scholar 

  • —, andJ. B. Brown: The assay of urinary gonadotrophins from men and from normally menstruating women in terms of Human Menopausal Gonadotrophin (HMG). J. Endocr.13, i (1955).

    Google Scholar 

  • — —: A method for the quantitative determination of gonadotrophins in the urine of non-pregnant human subjects. J. Endocr.18, 77 (1959).

    Google Scholar 

  • Mahesh, V. B., andR. B. Greenblatt: Physiology and pathogenesis of the Stein-Leventhal syndrome. Nature (Lond.)191, 888 (1961).

    Google Scholar 

  • — —: Isolation of dehydroepiandrosterone and 17α-hydroxy-Δ 5-pregnenolone from the polycystic ovaries of the Stein-Leventhal syndrome. J. clin. Endocr.22, 441 (1962).

    Google Scholar 

  • Maršalek, J., M. Talaš, D. Novosad u.L. Bartošova: Beitrag zur Differentialdiagnose des Hirsutismus. Arch. Gynäk.188, 443 (1957).

    Google Scholar 

  • Noall, M. W., F. Alexander andW. M. Allen: C19-steroid biosynthesis by human ovaries. Fed. Proc.21, 208 E (1962).

    Google Scholar 

  • Nocke, W.: A study of the colorimetric estimation of oestradiol-17β, oestradiol-17α, oestrone, oestriol and 16-epioestriol by the Kober-reaction. Biochem. J.78, 593 (1961).

    Google Scholar 

  • Norymberski, J. K.: Determination of urinary corticosteroids. Nature (Lond.)170, 1074 (1952).

    Google Scholar 

  • —,R. D. Stubbs andH. F. West: Assessement of adrenocortical activity by assay of 17-ketogenic steroids in urine. Lancet1953 I, 1276.

    Google Scholar 

  • Opitz, J. M., andE. Witschi: The polycystic ovary syndrome. Anat. Rec.134, 619 (1959).

    Google Scholar 

  • Paoli, J. de, andE. Nishizawa: Hydrolysis of urinary 17-ketosteroids (17-KS). Fed. Proc.21, 211 F (1962).

    Google Scholar 

  • Perloff, W. H., B. J. Channick, H. E. Hadd andJ. H. Nodine: The Stein-Leventhal ovary. A manifestation of hyperadrenocorticism. Fertil. and Steril.9, 247 (1958).

    Google Scholar 

  • Philipp, E., u.H.- H. Stange: Das polycystische Ovarium (Stein-Leventhal-Syndrom). Dtsch. med. Wschr.79, 1519 (1954).

    Google Scholar 

  • Pond, H.: 17-ketosteroid fractionation studies by a micro-chromatographic technique in endocrine disorders. J. Endocr.10, 202 (1954).

    Google Scholar 

  • Prader, A.: In: Klinik der inneren Sekretion,von A. Labhart. Berlin-Göttingen-Heidelberg: Springer 1957.

    Google Scholar 

  • Reddy, W.: Modification of the Reddy-Jenkins-Thorn method for the estimation of 17-hydroxycorticoids in urine. Metabolism3, 489 (1954).

    Google Scholar 

  • —,D. Jenkins andG. Thorn: Estimation of 17-hydroxycorticoid in urine. Metabolism1, 511 (1952).

    Google Scholar 

  • Roberts, K. D., R. L. van de Wiele andS. Lieberman: The conversion in vivo of dehydroandrosterone sulphate to androsterone and etiocholanolone glucuronidates. J. biol. Chem.236, 2213 (1961).

    Google Scholar 

  • Robinson, A. M., A. Dimoline andD. G. Jones: Consideration of some types of adrenal tumors. Ciba Found. Coll. Endocr.12, 137 (1958).

    Google Scholar 

  • Roy, M. van: Persönliche Mitteilungen 1962.

  • Ryan, K. J., andO. W. Smith: Biogenesis of estrogens by the human ovary. IV. Formation of neutral steroid intermediates. J. biol. Chem.236, 2207 (1961).

    Google Scholar 

  • Sachs, L.: Papierchromatographie der 17-Ketosteroide mit quantitativer Auswertung. Acta endocr. (Kbh.)38, 534 (1961).

    Google Scholar 

  • —: Haupttendenzen und Regulationsprinzipien der Steroidhormon-Biogenese. Arzneimittel-Forsch.12, 244 (1962).

    Google Scholar 

  • Sandor, T., andA. Lanthier: The in vitro transformation ofΔ 4-androstene-3,17-dione to testosterone by surviving human ovarian slices. Rev. canad. Biol.19, 445 (1960).

    Google Scholar 

  • Savard, K., M. Gut, R. I. Dorfman, J. L. Gabrilove andL. J. Soffer: Formation of androgens by human arrhenoblastoma tissue in vitro. J. clin. Endocr.21, 165 (1961).

    Google Scholar 

  • Schäfer, E. L.: Die Zuverlässigkeit einiger Funktionsprüfungen der Nebenniere. Dtsch. med. Wschr.86, 2257 (1961).

    Google Scholar 

  • Schteingart, M.: El cuadro clinico hormonal en la hipertricosis e hirsutismo. Pren. méd. argent.45, 22 (1958).

    Google Scholar 

  • Schubert, K.: Steroidstoffwechsel bei Brustkrebs. Acta endocr. (Kbh.)26, 173 (1957).

    Google Scholar 

  • Seeman, A., etR. T. Saracino: Contribution a l'étude de la formation de androgens par l'ovaire. Acta andocr. (Kbh.)37, 31 (1961).

    Google Scholar 

  • Short, R. V., and D. R.London: Defective biosynthesis of ovarian steroids in the Stein-Leventhal syndrome. Brit. med. J.1961, 1724.

  • Siebenmann, R. E.: Das adrenogenitale Syndrom. In: Klinik der inneren Sekretion,von A. Labhart. Berlin-Göttingen-Heidelberg: Springer 1957.

    Google Scholar 

  • Simmer, H., u.H. E. Voss: Androgene im menschlichen Ovarium. Klin. Wschr.38, 819 (1960).

    Google Scholar 

  • Staemmler, H.-J.: Der Einfluß gonadotroper Hormone auf ovarielle Fehlbildungen. Arch. Gynäk.187, 711 (1956).

    Google Scholar 

  • —: Über die postpartale Ovarial-Insuffizienz. Gynaecologia (Basel)145, 43 (1958).

    Google Scholar 

  • —: Über die Gonadotropin-Behandlung der Ovarial-Insuffizienz. Gynaecologia (Basel)146, 1 (1958).

    Google Scholar 

  • —: Sekundäre Amenorrhoe. Klassifizierung, Ergebnisse und Prognose nach Gonadotropin-Medikation. Dtsch. med. Wschr.85, 2062 (1960).

    Google Scholar 

  • —: Über die Zyklusinduktion exogener Gonadotropine (PMS-HCG). Z. Gynäk. Geburtsh.156, 144 (1961).

    Google Scholar 

  • - Die Anwendung von Gonadotropinen zur Regulation des Ovarialendokrinium. Berichte III. Weltkongreß für Gynäkologie und Geburtshilfe, Wien 3.-9. 9. 1961.

  • —: L'utilisation des gonadotrophines dans le diagnostic et le traitment de l'insuffisance ovarienne. Gynéc. prat.13, 145 (1962).

    Google Scholar 

  • Staib, E., u.W. Teller: Über die postpuberale Form des adrenogenitalen Syndroms. Biochemische Studien zur Frage einer partiellen Enzymstörung bei einem Fall von adrenogenitalem Syndrom. Klin. Wschr.37, 979 (1959).

    Google Scholar 

  • Stange, H.-H.: Zur Terminologie und Einteilung des konnatalen ovariellen Dysmorphismus. Geburtsh. u. Frauenheilk.18, 1263 (1958).

    Google Scholar 

  • Stein, I. F.: Bilateral polycystic ovaries. Significance in sterility. Amer. J. Obstet. Gynec.50, 385 (1945).

    Google Scholar 

  • —, andM. L. Leventhal: Amenorrhea associated with bilateral polycystic ovaries. Amer. J. Obstet. Gynec.29, 181 (1935).

    Google Scholar 

  • Trace, R. J., E. C. Keaty andM. L. McCall: An investigation of ovarian tissue and urinary 17-ketosteroids in patients with bilateral polyoystic ovaries. Amer. J. Obstet. Gynec.79, 310 (1960).

    Google Scholar 

  • Tropea, P. F.: Considerazioni cliniche e patogenetiche sull'irsutismo della donna. Riv. Ostet. Ginec.16, 344 (1961).

    Google Scholar 

  • —, eI. Coghi: Significatio clinico di un nuovo test semeiologico in endocrinologia. Riv. Ostet. Ginec.16, 398 (1961).

    Google Scholar 

  • Vague, J., A. Temine-Morhange, H. Payan, R. Muratore, J. C. Garrigues, J. Berthet etJ. Bonnet: Tumeur masculinisante de l'ovaire à cellules de Leydig. Étude clinique, anatomique et chimique. Ann. Endocr. (Paris)21, 437 (1960).

    Google Scholar 

  • Vermeulen, A., W. R. Slaunwhite jr. andA. A. Sandberg: Biliary and urinary metabolites of 4-C14-17α-hydroxyprogesterone in human subjects. J. clin. Endocr.21, 1534 (1961).

    Google Scholar 

  • Vestergaard, P., andB. Claussen: Hydrolysis of urinary 17-ketosteroid conjugates and estimation of the individual 17-ketosteroids by gradient elution chromatography. Acta endocr. (Kbh.), Suppl.64, 1 (1962).

    Google Scholar 

  • Voigt, K. D., A. Oriol-Bosch u.J. Tamm: Untersuchungen über den Einfluß einer intravenösen ACTH-Infusion auf die Plasma- und Urinsteroide von behandelten und unbehandelten Patienten mit Cushing-Syndrom. Klin. Wschr.38, 206 (1960).

    Google Scholar 

  • Warren, J. C., andH. A. Salhanick: Steroid biosynthesis in the human ovary. Clin. Endocr.21, 1218 (1961).

    Google Scholar 

  • Wilkins, L. M., E. A. Lewis, R. Klein andE. Rosemberg: The suppression of androgen secretion by cortisone in a case of congenital adrenal hyperplasia, preliminary report. Bull. Johns Hopk. Hosp.86, 249 (1950).

    Google Scholar 

  • Zander, J.: Steroids in the human ovary. J. biol. Chem.232, 117 (1958).

    Google Scholar 

  • —: Nachweis von Progesteron und 17α-Hydroxyprogesteron in hyperplastischen Nebennieren bei adrenogenitalem Syndrom. Klin. Wschr.38, 5 (1960).

    Google Scholar 

  • —: In vitro-Studien an Ovarien mit abnormer Hormonbildung. In Symposium über Krebsprobleme. Herausgeg. vonK. G. Ober, H. M. Rauen, J. Schoenmackers u.J. Zander, S. 90. Berlin-Göttingen-Heidelberg: Springer 1961.

    Google Scholar 

  • —, u.H. D. Henning: Hormone und Intersexualität. In: Die Intersexualität,von C. Overzier. Stuttgart: Georg Thieme 1961.

    Google Scholar 

  • —,W. G. Wiest u.K.- G. Ober: Klinische, histologische und biochemische Beobachtungen bei polycystischen Ovarien mit gleichzeitiger adenomatöser, atypischer Hyperplasie des Endometriums. Umwandlung von Progesteron-4-C14 im Ovarial-Gewebe. Arch. Gynäk.196, 481 (1962).

    Google Scholar 

  • Zerssen, D. v., A. E. Meyer u.D. Ahrens: Klinische, biochemische und psychologische Untersuchungen an Patientinnen mit gewöhnlichem Hirsutismus. Dtsch. Arch. klin. Med.206, 334 (1960).

    Google Scholar 

  • Zimmermann, H., u.H. Lins: Zur Differentialdiagnose und Therapie des idiopathischen Hirsutismus. Verh. dtsch. Ges. inn. Med.65, 174 (1959).

    Google Scholar 

  • Zimmermann, W.: Hormonbestimmungen bei Mamma- und Prostata-Carcinom. 7. Symp. Dtsch. Ges. Endokrinologie. Berlin-Göttingen-Heidelberg: Springer 1961, S. 67.

    Google Scholar 

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Staemmler, H.J., Sachs, L. Papierchromatographische Fraktionierung der C17-Ketosteroide bei Ovarial-Insuffizienz und verschiedenen Formen der Maskulinisierung. Arch. Gynak. 197, 612–658 (1963). https://doi.org/10.1007/BF00668404

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