Skip to main content
SpringerLink
Log in

Dietary habits and mammographic patterns in patients with breast cancer

  • Report
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

Summary

Between 1983 and 1986, dietary history interviews were conducted with 238 women aged 50–65 years who had surgery for stage I–II breast cancer. Diagnostic mammograms were coded in line with Wolfe's criteria in N1, P1, P2, and Dy patterns. Women with Dy pattern reported significantly higher intake of total fat, monounsaturated fatty acids (FA), polyunsaturated FA, n-3 FA, n-6 FA in per cent of energy (E%), and α-tocopherol in mg/10 MJ. Fat intake was lowest in women with N1 pattern and highest in those having Dy pattern. Patients having ER-rich cancers and Dy pattern reported significantly higher intake of total fat, monounsaturated FA, polyunsaturated FA, n-6 FA (E%), and α-tocopherol (mg/10 MJ), as well as significantly lower intake of carbohydrate (E%) and calcium (g/10 MJ). In the stepwise multivariate analysis, the multivariate-odds ratio (OR) for having P2 + Dy patterns was 1.06 (95% confidence interval (CI), 1.02–1.12) for each increment in E% of total fat. In women with ER-rich tumors this OR was 1.09 (95% CI, 1.02–1.16). The highest self-reported body mass index (BMI) was observed in women with N1 + P1 patterns. OR for having P2 + Dy patterns was 0.91 (95% CI, 0.83–0.98) for each increment in 1 kg/m2 of BMI. The results suggest that dietary habits affect the mammographic parenchymal pattern in women with breast cancer and that a high fat intake is associated with a higher proportion of mammograms with Dy pattern in such patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Buell P: Changing incidence of breast cancer in Japanese-American women. JNCI 51: 1479–1483, 1973

    Google Scholar 

  2. Prentice RL, Sheppard L: Validity of international, time trend and migrant studies in diet and cancer. Prev Med 18: 167–179, 1989

    Google Scholar 

  3. Rose DP, Boyar AP, Wynder EL: International comparison of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption. Cancer 58: 2363–2371, 1986

    Google Scholar 

  4. Boyd NF, Cousins M, Lockwood G, Tritchler D: Dietary fat and breast cancer risk: the feasibility of a clinical trial of breast cancer prevention. Lipids 27: 821–826, 1992

    Google Scholar 

  5. Howe GR, Hirohata T, Hislop TG, Iscovich JM, Yuan J-M, Katsouyanni K, Lubin F, Marubini E, Modan B, Rohan T, Toniolo P, Shunzhang Y: Dietary factors and risks of breast cancer: combined analysis of 12 case-control studies. JNCI 82: 561–569, 1990

    Google Scholar 

  6. Boyar AP, Rose DP, Wynder EL: Recommendation for the prevention of chronic disease: the application for breast disease. Am J Clin Nutr 48: 896–900, 1988

    Google Scholar 

  7. Willett WC, Stampfer MJ, Colditz GA, Rosner BA, Hennekens CH, Speizer FE: Dietary fat and the risk of breast cancer. N Engl J Med 316: 22–28, 1987

    Google Scholar 

  8. Gregorio DI, Emrich LJ, Graham S, Marshall JR, Nemoto T: Dietary fat consumption and survival among women with breast cancer. JNCI 75: 37–41, 1985

    Google Scholar 

  9. Papatestas AE, Knitle J, Lesnick G, Fagerstrom R, Mulvihill MN: Effect of dietary habits and lipids on prognosis in breast cancer. 3rd ECO Symposium, Aarhus, Denmark. Preresa, Brussels: European Organization for Cooperation in Cancer Prevention Studies, pp 66-67, 1985

  10. Verreault R, Brisson J, Deschênes L, Naud F, Meyer F, Bélanger L: Dietary fat in relation to prognostic indicators in breast cancer. JNCI 80: 819–825, 1988

    Google Scholar 

  11. Longnecker MP, Berlin JA, Orza MJ, Chalmers TC: A metaanalysis of alcohol consumption in relation to risk of breast cancer. J Amer Med Assoc 260: 652–656, 1988

    Google Scholar 

  12. Howe G, Rohan T, Decarli A, Isovich J, Kaldor J, Katsouyanni K, Marubini E, Miller A, Riboli E, Toniolo P, Trichopoulos D: The association between alcohol and breast cancer risk: Evidence from the combined analysis of six dietary case-control studies. Int J Cancer 47: 707–710, 1991

    Google Scholar 

  13. Boyd NF, O'Sullivan B, Campbell JE, Fishell E, Simor I, Cooke G, Germanson T: Mammographic signs as risk factors for breast cancer. Br J Cancer 45: 185–193, 1982

    Google Scholar 

  14. Wilkinson E, Clopton C, Gordonson J, Green R, Hill A, Pike MC: Mammographic parenchymal pattern and the risk of breast cancer. JNCI 59: 1397–1400, 1977

    Google Scholar 

  15. Wolfe JN: Risk for breast cancer development determined by mammographic parenchymal pattern. Cancer 37: 2486–2492, 1976

    Google Scholar 

  16. Wolfe JN: Breast patterns as an index of risk for developing breast cancer. AJR 126: 1130–1139, 1976

    Google Scholar 

  17. Brisson J, Morrison AS, Kopans DB, Sadowsky NL, Kalisher L, Twaddle JA, Meyer JE, Henschke CI, Cole P: Height and weight, mammographic features of breast tissue, and breast cancer risk. Am J Epidemiol 119: 371–381, 1984

    Google Scholar 

  18. Whitehead J, Carlile T, Kopecky KJ, Thompson DJ, Gilbert FI, Present AJ, Threatt BA, Krook P, Hadaway E: The relationship between Wolfe's classification of mammograms, accepted breast cancer risk factors, and the incidence of breast cancer. Am J Epidemiol 122: 994–1006, 1985

    Google Scholar 

  19. Holm L-E, Callmer E, Hjalmar M-L, Lidbrink E, Nilsson B, Skoog L: Dietary habits and prognostic factors in breast cancer. JNCI 81: 1218–1223, 1989

    Google Scholar 

  20. Nordevang E, Callmer E, Marmur A, Holm L-E: Dietary intervention in breast cancer patients: effects on food choice. Eur J Clin Nutr 46: 387–396, 1992

    Google Scholar 

  21. Wrange Ö, Nordenskjöld B, Gustafsson J-Å: Cytosol estradiol receptor in human mammary carcinoma: An assay based on isoelectric focusing in polyacrylamide gel. Anal Biochem 85: 416–421, 1978

    Google Scholar 

  22. Breslow NE, Day NE: Statistical methods in cancer research. Vol 1. The analysis of case-control studies. IARC Sci Publ No 32 Lyon: IARC 1980.

    Google Scholar 

  23. Brisson J, Verreault R, Marrison AS, Tennina S, Meyer F: Diet, mammographic features of breast tissue, and breast cancer risk. Am J Epidemiol 130: 14–24, 1989

    Google Scholar 

  24. Hinton CP, Roebuck EJ, Williams MR, Blamey RW, Glaves J, Nicholson RI, Griffiths K: Mammographic parenchymal patterns: Value as a predictor of hormone dependency and survival in breast cancer. AJR 144: 1103–1107, 1985

    Google Scholar 

  25. Rosenthal DI, Hall FM, Berenberg AL, Wyshak G, Burstein NA, Rosner AL: Correlation of estrogen receptors with mammography in breast cancer. Breast Dis Breast 6: 14–17, 1980

    Google Scholar 

  26. Nielsen NS, Poulsen HS: Relation between mammographic findings and hormonal receptor content in breast cancer. AJR 145: 501–504, 1985

    Google Scholar 

  27. Rose DP, Boyar AP, Cohen C, Strong LE: Effect of a low-fat diet on hormone levels in women with cystic breast disease. I. Serum steroids and gonadotropins. JNCI 78: 623–626, 1987

    Google Scholar 

  28. Prentice R, Thompson D, Clifford C, Gorbach S, Goldin B, Byar D: Dietary fat reduction and plasma estradiol concentration in healthy postmenopausal women. JNCI 82: 129–134, 1990

    Google Scholar 

  29. Longcope C, Gorbach S, Goldin B, Woods M, Dwyer J, Morrill A, Warram J: The effect of a low fat diet on estrogen metabolism. J Clin Endocrinol Metab 64: 1246–1250, 1987

    Google Scholar 

  30. Boyd NF, McGuire V, Fishell E, Kuriov V, Lockwood G, Tritchley D: Plasma lipids in premenopausal women with mammographic dysplasia. Br J Cancer 59: 766–771, 1989

    Google Scholar 

  31. Grove JS, Goodman MJ, Gilbert F, Clyde D: Factors associated with breast structure in breast cancer patients. Cancer 43: 1895–1899, 1979

    Google Scholar 

  32. Gravelle IH, Bulstrode JC, Bullbrook RD, Hayward JL, Wang DY: The relation between radiological patterns of the breast and body weight and height. Br J Radiol 55: 23–25, 1982

    Google Scholar 

  33. Lubin F, Ruder AM, Wax Y, Modan B: Overweight and changes in weight throughout adult life in breast cancer etiology. Am J Epidemiol 122: 579–588, 1985

    Google Scholar 

  34. Grove JS, Goodman MJ, Gilbert FI, Mi MP: Factors associated with mammographic pattern. Br J Radiol 58: 21–25, 1985

    Google Scholar 

  35. De Waard F, Rombach JJ, Collette HJA, Slotboom B: Breast cancer risk associated with reproductive factors and breast parenchymal patterns. JNCI 72: 1277–1282, 1984

    Google Scholar 

  36. Schoeller DA, Bandini LG, Dietz WH: Inaccuracies in self-reported intake identified by comparison with the doubly labelled water method. Can J Physiol Pharmacol 68: 941–949, 1990

    Google Scholar 

  37. Bandini LG, Schoeller DA, Cyr HN, Dietz WH: Validity of reported energy intake in obese and nonobese adolescents. Am J Clin Nutr 52: 421–425, 1990

    Google Scholar 

  38. Prentice AM, Black AE, Coward WA, Davies HL, Goldberg GR, Murgatroyd PR, Ashford J, Sawyer M, Whitehead RG: High levels of energy expenditure in obese women. Br Med J 292: 983–987, 1986

    Google Scholar 

  39. Gravelle IH, Bulstrode JC, Wang DY, Bulbrook RD, Hayward JL: The relation between radiographic features and determinants of risk of breast cancer. Br J Radiol 53: 107–113, 1980

    Google Scholar 

  40. Gravelle IH, Bulstrode JC, Bullbrook RD, Wang DY, Allen D, Hayward JL: A prospective study of mammographic parenchymal patterns and risk of breast cancer. Br J Radiol 59: 487–491, 1986

    Google Scholar 

  41. Andersson I, Janzon L, Pettersson H: Radiographic patterns of mammary parenchyma. Radiology 138: 59–62, 1981

    Google Scholar 

  42. Goldin BR, Adlercreutz H, Gorbach SL, Warram JH, Dwyer JT, Swenson L, Woods MN: Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. N Engl J Med 307: 1542–1547, 1982

    Google Scholar 

  43. Armstrong BK, Brown JB, Clarke HT, Crooke DK, Hähnel R, Masarei JR, Ratajczak T: Diet and reproductive hormones: a study of vegetarian and nonvegetarian postmenopausal women. JNCI 67: 761–767, 1981

    Google Scholar 

  44. Sporn MB, Dunlop NM, Newton DL, Smith JM: Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids). Fed Proc 35: 1332–1338, 1976

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cancer Prevention, Radiumhemmet Karolinska Hospital, S-104 01, Stockholm, Sweden

    E. Nordevang

  2. Department of Diagnostic Radiology, Radiumhemmet Karolinska Hospital, S-104 01, Stockholm, Sweden

    E. Azavedo & G. Svane

  3. Department of Cancer Epidemiology, Radiumhemmet Karolinska Hospital, S-104 01, Stockholm, Sweden

    B. Nilsson

  4. National Institute of Public Health, Stockholm, Sweden

    L-E. Holm

Authors
  1. E. Nordevang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Azavedo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. Svane
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. B. Nilsson
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L-E. Holm
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nordevang, E., Azavedo, E., Svane, G. et al. Dietary habits and mammographic patterns in patients with breast cancer. Breast Cancer Res Tr 26, 207–215 (1993). https://doi.org/10.1007/BF00665798

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00665798

Key words

Search

Navigation