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Allograft in the treatment of benign cystic lesions of bone

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Summary

Seventeen patients with benign cystic osseous lesions were treated by curettage and grafting using allogenic decalcified bone. Human bones were partially decalcified using 0.6N HCl and preserved in 90% ethanol in a deep freezer at -16°C. The cystic lesions were: 5 cases of fibrous dysplasia, 4 aneurysmal bone cysts, 3 simple bone cysts, 2 giant-cell tumours, 1 chondromyxoid fibroma, 1 non-ossifying fibroma and 1 fibrous cortical defect. The bones involved were: femur, tibia, humerus, fibula and calcaneum. Infection was a complication in three patients. In two of these it did not interfere with healing, but in one it persisted for more than 1 year with partial resorption of the graft. The time to adequate incorporation of the graft varied from 6 to 9 months in children and 9 to 15 months in adults. The overall response compares favourably with that to allograft from more sophisticated bone banks.

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Sethi, A., Agarwal, K., Sethi, S. et al. Allograft in the treatment of benign cystic lesions of bone. Arch Orthop Trauma Surg 112, 167–170 (1993). https://doi.org/10.1007/BF00662282

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