Abstract
A girl, 12 years of age, was referred for short stature. Clinical examination and laboratory investigations currently performed in a case of growth failure gave normal results. Renal echography revealed a hyper-echogenic renal medulla. An excretory urogram showed medullary sponge kidney with bilateral renal calculi. An ammonium chloride loading test revealed a defect in acid excretion and led to the diagnosis of incomplete renal tubular acidosis. Treatment with oral bicarbonate was associated with an increase in growth velocity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
albright F, Consolazio WV, Coombs FS (1940) Metabolic studies and therapy in a case of nephrocalcinosis with ricketts and dwarfism. Bull Johns Hopkins Hosp 66: 7–33
Baran DT, Lee SW, Jo OD (1982) Acquired alteration in vitamin-D metabolism in the acidotic state. Calcif Tissue Int 34:165–177
Buckalew UM, McCurdy DK, Ludwig GD, Chaykin LB, Elkinton JR (1968) Incomplete renal tubular acidosis. Physiologic studies in three patients with a defect in lowering urine pH. Am J Med 45:40
Butler AM, Wilson JL, Farber S (1936) Dehydratation and acidosis with calcification of renal tubules. J Pediatr 8:489–499
Cacchi R, Ricci V (1949) Sur une rare maladie kystique multiple des pyramides rénales, le rein en éponge. J Urol 55:497–519
Chan JCM (1983) Renal tubular acidosis. J Pediatr 102 (3) 327–340
Deck MDF (1965) Medullary sponge kidney with renal tubular acidosis: a report of 3 cases. J Urol 94:330–335
Kumagai I, Matsuo S, Kato T (1980) A case of incomplete renal tubular acidosis (type 1) associated with medullary sponge kidney, followed by nephrocalcinosis. J Urol 123:250–252
Levine AS, Michael AF (1967) Ehler-Danlos syndrome with renal tubular acidosis and medullary sponge kidneys. J Pediatr 71:107–113
McSherry E, Morris RC (1978) Attainment and maintenance of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. J Clin Invest 61:509–527
Morris C, Yamauchi H, Palibinskas AS, Howenstine J (1963) Medullary sponge kidney. Am J Med 38:883–891
Popa M, Stanescu V (1969) Renal tubular acidosis and hypergammaglobulinaemic purpura in a 10-year-old girl with roentgenographic signs suggesting medullary sponge kidney. Acta Paediatr Scand 58: 290–294
Stickler GB, Bergen BJ (1973) A review: short stature in renal disease. Pediatr Res 7:978–982
Wrong O, Davies ME (1959) The excretion of acid in renal diseases. Q J Med 28:259–268
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sluysmans, T., Vanoverschelde, J.P. & Malvaux, P. Growth failure associated with medullary sponge kidney, due to incomplete renal tubular acidosis type 1. Eur J Pediatr 146, 78–80 (1987). https://doi.org/10.1007/BF00647294
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00647294