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Epidural lipomatosis: case report and literature review

  • Diagnostic Neuroradiology
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Abstract

We report a case of symptomatic epidural lipomatosis in a 36-year-old man following a heart lung transplant and 3.5 years of steroid medication. A review of the pertinent literature emphasises the importance of including this diagnosis in the differential diagnosis of patients receiving steroid medication or markedly obese patients with back pain or symptoms suggesting spinal cord or cauda equina compression.

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References

  1. Cushing H (1932) The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism). Bull Johns Hopkins Hosp 50: 137–195

    Google Scholar 

  2. Plotz CM, Knowltor AI, Ragan C (1952) The natural history of Cushing's syndrome. Am J Med 13: 597–614

    Google Scholar 

  3. Lee M, Lekias J, Gubbay SS, Hurst PE (1975) Spinal cord compression by extradural fat after renal transplantation. Med J Aust 1: 201–203

    Google Scholar 

  4. Lipson SJ, Naheedy MH, Kaplan MM, Bienfang DC (1989) Spinal stenosis caused by epidural lipomatosis in Cushing's syndrome. N Engl J Med 302: 36

    Google Scholar 

  5. Guegan Y, Fardoun R, Launois B, Pecker J (1982) Spinal cord compression by extradural fat after prolonged corticosteroid therapy. J Neurosurg 56: 267–269

    Google Scholar 

  6. Archer CR, Smith KR (1982) Extradural lipomatosis simulating an acute herniated nucleus pulposus. J Neurosurg 57: 559–562

    Google Scholar 

  7. George WE, Wilmot M, Greenhouse A, Hammeke M (1983) Medical management of steroid-induced epidural lipomatosis. N Engl J Med 308: 316–319

    Google Scholar 

  8. Randall BC, Muraki AS, Osborn RE, Brown F (1986) Epidural lipomatosis with lumbar radiculopathy: CT appearance. J Comput Assist Tomogr 10: 1039–1041

    Google Scholar 

  9. Haid RW, Kaufmann HH, Schochet SS, Marano GD (1987) Epidural lipomatosis simulating an epidural abscess: case report and literature review. Neurosurgery 21: 744–747

    Google Scholar 

  10. Jungreis CA, Cohen WA (1987) Spinal cord compression induced by steroid therapy: CT findings. J Comput Assist Tomogr 11: 245–247

    Google Scholar 

  11. Zampella EJ, Duvall ER, Sekar C, Langford KH, Epstein AE, Kirklin JK, Morawetz RB (1987) Symptomatic spinal epidural lipomatosis as a complication of steroid immunosuppression in cardiac transplant patients. J Neurosurg 67: 760–764

    Google Scholar 

  12. Quint DJ, Boulos RS, Sanders WP, Mehta BA, Patel SC, Tiel RL (1988) Epidural lipomatosis. Radiology 169: 485–490

    Google Scholar 

  13. Bednar DA, Esses SI, Kucharczyk W (1990) Symptomatic lumbar epidural lipomatosis in a normal male. Spine 15: 52–53

    Google Scholar 

  14. Roy-Camille R, Mazel C, Husson JL, Saillant G (1991) Symptomatic spinal epidural lipomatosis induced by longterm steroid treatment. Spine 16: 1365–1371

    Google Scholar 

  15. Marks SM (1991) Epidural lipomatosis. J Neurosurg 75: 669

    Google Scholar 

  16. Peeters FLM, Koster PA (1991) Epidural lipomatosis simulating spinal canal stenosis or herniated nucleus pulposus. Fortschr Röntgenstr 154: 342–343

    Google Scholar 

  17. Haddad SF, Hitchon PW, Godersky TC (1991) Idiopathic and glucocorticoid-induced spinal epidural lipomatosis. J Neurosurg 74: 38–42

    Google Scholar 

  18. Fessler RG, Johnson DL, Brown FD, Erickson RK, Reid SA, Kranzler L (1991) Epidural lipomatosis in steroidtreated patients Spine 17: 183–188

    Google Scholar 

  19. Beges C, Rousselin B, Godefroy A, Vallee C, Berenbaum F, Deshays C, Amor B (1944) Epidural lipomatosis. Interest of magnetic resonance imaging in a weight-reduction treated case. Spine 19: 251–254

    Google Scholar 

  20. Godeau P, Brunet P, Wechsler B, Fohanno D (1979) Lipomatose extradurale compressive accident inhabituel de la corticothèrapie. Nouv Presse Mèd 8: 3889–3891

    Google Scholar 

  21. Butcher DL, Sahn SA (1979) Epidural lipomatosis: a complication of corticosteroid therapy. Ann Intern Med 90:60

    Google Scholar 

  22. Chapman PH, Martuza RL, Poletti CE, Karchmer AW (1981) Symptomatic spinal epidural lipomatosis associated with Cushing's syndrome. Neurosurgery 8: 724–727

    Google Scholar 

  23. Russel NA, Belanger G, Benoit BG (1984) Spinal epidural lipomatosis: a complication of glucocorticoid therapy. Can J Neurol Sci 11: 383–386

    Google Scholar 

  24. Badami JP, Hinck VC (1982) Symptomatic deposition of epidural fat in a morbidly obese woman. AJNR 3: 664–665

    Google Scholar 

  25. Haddad S, Hitchon P, Godersky JC (1991) Epidural lipomatosis. J Neurosurg 75: 669

    Google Scholar 

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Hierholzer, J., Benndorf, G., Lehmann, T. et al. Epidural lipomatosis: case report and literature review. Neuroradiology 38, 343–348 (1996). https://doi.org/10.1007/BF00596585

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  • DOI: https://doi.org/10.1007/BF00596585

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