Skip to main content
Log in

Neuroradiologic findings in leptomeningeal carcinomatosis: the value interest of gadolinium-enhanced MRI

  • Originals
  • Published:
Neuroradiology Aims and scope Submit manuscript

Summary

Four patients with leptomeningeal metastases documented by neuroradiological examinations are reported. All had central nervous system or systemic neoplasms and showed clinical signs of carcinomatous meningitis. Gadolinium-enhanced MRI (Gd-MRI) disclosed for each patient pathological foci, allowing delineation of the extent of meningeal disease. Although non-specific, these findings, combined with the clinical context and CSF analysis, may lead to a rapid diagnosis and treatment of carcinomatous meningitis, even when malignant cells are not detected in the cerebrospinal fluid.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Wasserstrom WR, Glass JP, Posner JB (1982) Diagnosis and treatment of leptomeningeal metastases from solid tumors. Experience with 90 patients. Cancer 49:759–772

    Google Scholar 

  2. Seeldrayers P, Hildebrand J (1984) Treatment of neoplastic meningitis. Eur J Cancer Clin Oncol 20:449–456

    Google Scholar 

  3. Glass JP, Melamed M, Chernik N, Posner JB (1979) Malignant cells in cerebrospinal fluid (CSF): the meaning of a positive CSF cytology. Neurology 29:1369–1375

    Google Scholar 

  4. Davis P, Friedmann N, Fry St, Malko J, Hoffmann J, Braun I (1987) Leptomeningeal metastasis: MR imaging. Radiology 163:449–454

    Google Scholar 

  5. Krol G, Sze G, Malkin M, Walker R (1988) MR of cranial and spinal meningeal carcinomatosis: comparison with CT and myelography. AJNR 9:709–714

    Google Scholar 

  6. Brown E, De La Paz R (1989) Enhancement of meningeal lesions with gadopentetate (Gd-DTPA) MRI. 27th Annual Meeting of the American Society of Neuroradiology, Orlando, March 1989. Bood of Abstracts, p 64; AJNR 10:877

  7. Sze G, Bronen R, Krol G (1989) MR of the meninges with emphasis on meningeal carcinomatosis. AJNR 10:965–975

    Google Scholar 

  8. Parizel P, Baleriaux D, Rodesch G, Segebarth Chr, Lalmand B, Christophe C, Lemort M, Haesendonck Ph, Niendorf HP, Flament Durand J, Brotchi J (1989) Gd-DTPA enhanced MRI imaging of spinal tumors. AJNR 10:249–258

    Google Scholar 

  9. Fredericks R, Elster A, Walker F (1989) Gadolinium-enhanced MRI: a superior technique for the diagnosis of intraspinal metastases. Neurology 39:734–736

    Google Scholar 

  10. Mathews V, Kuharik M, Edwards M, D'Amour P, Azzarelli B, Dreesen RG (1988) Gd-DTPA-enhanced MR imaging of experimental bacterial meningitis: evaluation and comparison with CT. AJNR 9:1045–1050

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rodesch, G., Van Bogaert, P., Mavroudakis, N. et al. Neuroradiologic findings in leptomeningeal carcinomatosis: the value interest of gadolinium-enhanced MRI. Neuroradiology 32, 26–32 (1990). https://doi.org/10.1007/BF00593937

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00593937

Key words

Navigation