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Pneumocephalus due to nasopharyngeal carcinoma: case report

  • Head and Neck Radiology
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Abstract

A 55-year-old man with recurrent nasopharyngeal carcinoma presented with intractable headaches and intermittent rhinorrhoea for 2 weeks. CT showed severe destruction of the skull base by the tumour. The headache persisted despite intraventricular morphine. On the 29th hospital day, sudden onset of neurological deterioration led to coma, and CT revealed tension pneumocephalus due to nasopharyngeal carcinoma breaking through the skull base. The literature on pneumocephalus is reviewed and the aetiology discussed.

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References

  1. Chiari H (1884) Ueber einen Fall von Luftansammlung in den Ventrikeln des menschlichen Gehirns. Z Heilkd 5: 383–390

    Google Scholar 

  2. Luckett WH (1913) Air in the ventricles of the brain, following a fracture of the skull: report of a case. Surg Gynecol Obstet 17: 237–240

    Google Scholar 

  3. Markham JW (1967) The clinical features of pneumocephalus based upon a survey of 284 cases with report of additional cases. Acta Neurochir 16: 1–78

    Google Scholar 

  4. Arbit E, Shah J, Redford R (1991) Tension pneumocephalus: treatment with controlled decompression via a closed water-seal drainage system. J Neurosurg 74: 139–142

    Google Scholar 

  5. Betz H, Prager P (1981) Spontaneous pneumatocele during radiation of a giant meningosarcoma. Neuroradiology 22: 159–161

    Google Scholar 

  6. Bremer AM, Nguyen TQ (1982) Tension pneumocephalus after surgical treatment of chronic subdural hematoma: a report of three cases. Neurosurgery 11: 284–287

    Google Scholar 

  7. Davis DH, Laws ER Jr, McDonald TJ (1981) Intraventricular tension pneumocephalus as a complication of paranasal sinus surgery. Neurosurgery 8: 574–576

    Google Scholar 

  8. Goldman RW (1986) Pneumocephalus as a consequence of barotrauma. JAMA 255: 3154–3156

    Google Scholar 

  9. Pitt TE (1982) Intracranial aerocele in facial injury. Med J Aust 1: 499–502

    Google Scholar 

  10. Raggio JF, Fleischer AS, Sung UF (1979) Expanding pneumocephalus due to nitrous oxide anesthesia: case report. Neurosurgery 4: 261–263

    Google Scholar 

  11. Taguchi Y, Sato J, Nakamura N (1981) Gas-containing brain abscess due toFusobacterium nucleatum. Surg Neurol 16: 408–410

    Google Scholar 

  12. Walker FO, Vern BA (1986) The mechanism of pneumocephalus formation in patients with CSF fistulas. J Neurol Neurosurg Psychiatry 49: 203–205

    Google Scholar 

  13. Clark JB, Six EG (1984) Epidermoid tumor presenting as tension pneumocephalus. J Neurosurg 60: 1312–1314

    Google Scholar 

  14. Isler RJ, Weber AL (1978) Pneumocephalus from paranasal sinus carcinoma. Ann Otol 87: 142–143

    Google Scholar 

  15. Kinsley S, Dougherty J (1993) Tension pneumocephalus related to an epidermoid tumor of ethmoid sinus origin. Ann Emerg Med 22: 259–61

    Google Scholar 

  16. Wilson ES Jr, Sheft DJ (1986) Epidermoid tumor of the skull with intracranial pneumatocele: case report. J Neurosurg 28: 600–602

    Google Scholar 

  17. Neel HB III (1985) Nasopharyngeal carcinoma: clinical presentation, diagnosis, treatment, and prognosis. Otolaryngol Clin North Am 18: 479–493

    Google Scholar 

  18. Lishner M, Perrin RG, Feld R, et al (1990) Complication associated with Ommaya reservoirs in patients with cancer. Arch Intern Med 150: 173–176

    Google Scholar 

  19. Obbens EAMT, Leavens ME, Beal JW, et al (1985) Ommaya reservoirs in 387 cancer patients: a 15-year experience. Neurology 35: 1274–1278

    Google Scholar 

  20. Bedwinek JM, Skukovsky IJ, Fletcher GH, et al (1976) Osteonecrosis in patients treated with definitive radiotherapy for squamous cell carcinomas of oral cavity and naso- and oropharynx. Radiology 119: 665–667

    Google Scholar 

  21. Morrish R, Chan E, Silverman S, et al (1981) Osteoradionecrosis in patients irradiated for head and neck carcinoma. Cancer 47: 1980–1983

    Google Scholar 

  22. Frankel M, Faley D, Alker G (1980) Otogenic pneumocephalus secondary to chronic otitis media. Arch Otolaryngol 196: 437–439

    Google Scholar 

  23. Gilbert A, Tolmach R, Farrell J (1961) Gas gangrene of the brain. Am J Surg 101: 366–369

    Google Scholar 

  24. Osborn AG, Daines JH, Wing SD (1978) Intracranial air on computerized tomography. J Neurosurg 48: 355–359

    Google Scholar 

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Kiu, M.C., Wan, Y.L., Ng, S.H. et al. Pneumocephalus due to nasopharyngeal carcinoma: case report. Neuroradiology 38, 70–72 (1996). https://doi.org/10.1007/BF00593227

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  • DOI: https://doi.org/10.1007/BF00593227

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